Browsing by Author "Kiarie, James"
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Changes in Glomerular Kidney Function Among HIV-1– Uninfected Men andWomen Receiving Emtricitabine– Tenofovir Disoproxil Fumarate Preexposure Prophylaxis A Randomized Clinical Trial
Mugwanya, Kenneth K.; Wyatt, Christina; Celum, Connie; Donnell, Deborah; Mugo, Nelly R.; Tappero, Jordan; Kiarie, James; Ronald, Allan; Baeten, Jared M. (JAMA Internal Medicine, 2014-12)IMPORTANCE Tenofovir disoproxil fumarate (TDF) use has been associated with declines in the estimated glomerular filtration rate (eGFR) when used as part of antiretroviral treatment by persons with human immunodeficiency ... -
Characteristics of HIV-1 discordant couples enrolled in a trial of HSV-2 suppression to reduce HIV-1 transmission: the partners study.
Mugo, Nelly; Lingappa, Jairam R.; Kahle, Erin; Mujugira, Andrew; Magaret, Amalia; Baeten, Jared; Bukusi, Elizabeth A.; Cohen, Craig R.; Katabira, Elly T.; Ronald, Allan; Kiarie, James; Farquhar, Guy; Stewart, Grace John; Makhema, Joseph; Essex, M.; Were, Edwin; Fife, Kenneth (Public Library of Science, 2009-04-30)Background: The Partners HSV-2/HIV-1 Transmission Study (Partners Study) is a phase III, placebo-controlled trial of daily acyclovir for genital herpes (HSV-2) suppression among HIV-1/HSV-2 co-infected persons to reduce ... -
Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study
Heff ron, Renee; Donnell, Deborah; Rees, Helen; Celum, Connie; Mugo, Nelly; Were, Edwin; de Bruyn, Guy; Nakku-Joloba, Edith; Ngure, Kenneth; Kiarie, James; Coombs, Robert W.; Baeten, Jared M. (Elsevier, 2012-01-01)Background Hormonal contraceptives are used widely but their eff ects on HIV-1 risk are unclear. We aimed to assess the association between hormonal contraceptive use and risk of HIV-1 acquisition by women and HIV-1 ...