Browsing by Subject "Xpert MTB/RIF"

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Improving the Sensitivity of the Xpert MTB/RIF Assay on sputum pellets by decreasing the amount of added sample reagent: a laboratory and clinical evaluation

Dharan, Nila J.; Amisano, Danielle; Mboowa, Gerald; Ssengooba, Willy; Blakemore, Robert; Kubiak, Rachel W.; Armstrong, Derek T.; Jones, Martin; Manabe, Yukari C.; Joloba, Moses L.; Ellner, Jerrold J.; Dorman, Susan E.; Alland, David (American Society for Microbiology, 2015)

The Xpert MTB/RIF(Xpert) assay permits rapid near-patient detection of Mycobacterium tuberculosis in sputum; however, the test sensitivity remains suboptimal in paucibacillary specimens that are negative for acid-fast ...