Now showing items 1-6 of 6

    • Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: A prospective cohort study 

      Boulware, David R.; Meya, David B.; Bergemann, Tracy L.; Wiesner, Darin L.; Rhein, Joshua; Musubire, Paul; Lee, Sarah J.; Kambugu, Andrew; Janoff, Edward N.; Bohjanen, Paul R. (PLoS Medicine, 2010)
      Background: Although antiretroviral therapy (ART) improves survival in persons with cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution inflammatory syndrome (IRIS), an exaggerated and ...
    • Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy 

      Kambugu, Andrew; Meya, David B.; Rhein, Joshua; O’Brien, Meagan; Janoff, Edward N.; Ronald, Allan R.; Kamya, Moses R.; Mayanja-Kizza, Harriet; Sande, Merle A.; Bohjanen, Paul R.; Boulware, David R. (CID, 2008)
      Background. Cryptococcal meningitis (CM) is the proximate cause of death in 20%–30% of persons with acquired immunodeficiency syndrome in Africa. Methods. Two prospective, observational cohorts enrolled human immunodeficiency ...
    • Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis 

      Boulware, David R.; Meya, David B.; Conrad, Muzoora; Rolfes, Melissa A.; Hullsiek, Katherine Huppler; Musubire, Abdu; Taseera M., Kabanda; Nabeta, Henry W.; Schutz, Charlotte; Williams, Darlisha A.; Rajasingham, Radha; Rhein, Joshua; Thienemann, Friedrich; Lo, Melanie W.; Nielsen, Kirsten; Bergemann, Tracy L.; Kambugu, Andrew; Munabe, Yukari C.; Janoff, Edward N.; Bohjanen, Paul R.; Meintjes, Graeme (The New England Journal of Medicine, 2014)
      Background Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; however, the question of when ART should ...
    • Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis 

      Boulware, David R.; Meya, David B.; Muzoora, Conrad; Rolfes, Melissa A.; Hullsiek, Katherine Huppler; Musubire, Abdu; Taseera, Kabanda; Nabeta, Henry W.; Schutz, Charlotte; Williams, Darlisha A; Rajasingham, Radha; Rhein, Joshua; Thienemann, Friedrich; Lo, Melanie W; Nielsen, Kirsten; Bergemann, Tracy L.; Kambugu, Andrew; Manabe, Yukari C.; Janoff, Edward N.; Bohjanen, Paul R.; Meintjes, Graeme (Massachusetts Medical Society, 2014)
      Background Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; however, the question of when ART should ...
    • Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings 

      Meintjes, Graeme; Lawn, Stephen D.; Scano, Fabio; Maartens, Gary; French, Martyn A.; Worodria, William; Elliott, Julian H.; Murdoch, David; Wilkinson, Robert J.; Seyler, Catherine; John, Laurence; van der Loeff, Maarten Schim; Reiss, Peter; Lynen, Lut; Janoff, Edward N.; Gilks, Charles; Colebunders, Robert (Elsevier, 2008-08)
      The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important early complication of antiretroviral therapy (ART) in resource-limited settings, especially in patients with tuberculosis. However, there ...
    • Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings 

      Meintjes, Graeme; Lawn, Stephen D.; Scano, Fabio; Maartens, Gary; French, Martyn A.; Worodria, William; Elliott, Julian H.; Murdoch, David; Wilkinson, Robert J.; Seyler, Catherine; John, Laurence; Lynen, Lut; Janoff, Edward N.; Gilks, Charles; Colebunders, Robert; van der Loeff, Maarten Schim (Elsevier, 2008-08)
      The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important early complication of antiretroviral therapy (ART) in resource-limited settings, especially in patients with tuberculosis. However, there ...