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Now showing items 11-20 of 29
Symptomatic hyperlactatemia associated with nucleoside analogue reverse-transcriptase inhibitor use in HIV-infected patients: a report of 24 cases in a Resource-Limited Setting (Uganda).
(University of Chicago Press, 2007)
We describe 24 Ugandan patients with human immunodeficiency virus infection who developed symptomatic hyperlactatemia associated with the use of nucleoside analogues. All patients were receiving combination therapy that ...
Update on the efficacy, effectiveness and safety of artemether–lumefantrine combination therapy for treatment of uncomplicated malaria
(Dove Medical Press, 2009)
Artemether–lumefantrine is one of the artemisisnin-based combination therapies recommended for treatment of uncomplicated falciparum malaria. The drug combination is highly efficacious against sensitive and multidrug ...
Integration of HIV and TB services results in improved TB treatment outcomes and earlier prioritized ART initiation in a large urban HIV clinic in Uganda
(Lippincott, Williams & Wilkins, 2012-06-01)
Background: The World Health Organization recommends that treatment of tuberculosis ...
In reply to `Empirical tuberculosis treatment or improved diagnostics?'
(International Union Against Tuberculosis and Lung Disease, 2012-02-16)
We read the article by Lawn and colleagues with great interest. Atypical presentation and limited diagnostic capability in resource-limited settings lead to delays in treatment that could contribute to high rates of ...
Evaluation of Dynabeads and Cytospheres Compared With Flow Cytometry to Enumerate CD41 T Cells in HIV-Infected Ugandans on Antiretroviral Therapy
(Lippincott Williams & Wilkins., 2008-07-01)
Background: Laboratory-based monitoring of antiretroviral therapy is essential but adds a significant cost to HIV care. The World Health Organization 2006 guidelines support the use of CD4 lymphocyte count (CD4) to define ...
Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings
(Elsevier, 2008-08)
The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important early complication of antiretroviral therapy (ART) in resource-limited settings, especially in patients with tuberculosis. However, there ...
Can response of a pruritic papular eruption to antiretroviral therapy be used as a clinical parameter to monitor virological outcome?
(Lippincott Williams & Wilkins, 2008)
Background: A pruritic papular eruption (PPE) is a common skin manifestation observed in 12–46% of persons with HIV infection living in tropical countries. Objective: To determine whether PPE responds to HAART and whether ...
Cause-Specific Mortality and the Contribution of Immune Reconstitution Inflammatory Syndrome in the First 3 Years after Antiretroviral Therapy Initiation in an Urban African Cohort
(Infectious Diseases Society of America, 2009)
Background. Although many studies have reported high early mortality among patients enrolled in antiretroviral therapy (ART) programs in sub-Saharan Africa—particularly among those individuals with advanced immunodeficiency— ...
Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?
(Open Learning on Enteric Pathogens, 2009-03)
A large number of patients are switched to second-line antiretroviral therapy, especially in resource limited settings. Lopinavir/Ritonavir is the main drug used in second-line treatment regimens. We describe a patient ...
The TB pandemic: an old problem seeking new solutions
(Blackwell, 2007)
Tuberculosis (TB) continues to kill more than 2 million people globally each year. Annual TB case notification rates have risen up to fourfold since the mid-1980s, with the highest rate of 1000/100 000 around Cape Town, ...