Browsing College of Health Sciences (CHS) by Author "Joloba, Moses"
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Community-acquired pnemonia in Ugandan adults: short-term parenteral ampicilin therapy for bacterial pnemonia
Yoshimine, Hiroyuki; Oishi, Kazunori; Mubiru, Francis; Nalwoga, Hawa; Takahashi, Hidehiko; Amano, Hideaki; Ombasi, Philip; Watanabe, Kiwao; Joloba, Moses; Aisu, Thomas; Ahmed, Kamruddin; Shimada, Masaaki; Mugerwa, Roy; Nagatake, Tsuyoshi (American Society of Tropical Medicine and Hygiene, 2001)A hospital-based prospective study of 99 patients with community-acquired pneumonia (CAP) was carried out in Kampala, Uganda. We evaluated microbiological etiologies, clinical features and effectiveness of short-term ... -
Community-acquired pneumonia in Ugandan adults: short-term parenteral ampicillin therapy for bacterial pneumonia
Yoshimine, Hiroyuki; Oishi, Kazunori; Mubiru, Francis; Takahashi, Hidehiko; Amano, Hideaki; Ombasi, Philip; Watanabe, Kiwao; Joloba, Moses; Aisu, Thomas; Ahmed, Kamruddin; Shimada, Masaaki; Mugerwa, Roy; Nagatake, Tsuyoshi (The American Society of Tropical Medicine and Hygiene, 2001)A hospital-based prospective study of 99 patients with community-acquired pneumonia (CAP) was carried out in Kampala, Uganda. We evaluated microbiological etiologies, clinical features and effectiveness of short term ... -
Complexity of plasmodium falciparum clinical samples from Uganda during short-term culture.
Nsobya, Samuel L.; Kiggundu, Moses; Joloba, Moses; Dorsey, Grant; Rosentha, Philip J. (University of Chicago Press, 2008-08-22)We cultured Plasmodium falciparum parasites from 98 Ugandan children with malaria and determined the complexity of infection (COI) on the basis of msp-2 polymorphisms daily for 9 days. The mean COI decreased during culture ... -
Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing
Clark, Taane G.; Mallard, Kim; Coll, Francesc; Preston, Mark; Assefa, Samuel; Harris, David; Ogwang, Sam; Mumbowa, Francis; Kirenga, Bruce; O’Sullivan, Denise M.; Okwera, Alphonse; Eisenach, Kathleen D.; Joloba, Moses; Bentley, Stephen D.; Ellner, Jerrold J.; Parkhill, Julian; Jones- López, Edward C.; McNerney, Ruth (PLOS One, 2013)Background: Understanding the emergence and spread of multidrug-resistant tuberculosis (MDR-TB) is crucial for its control. MDR-TB in previously treated patients is generally attributed to the selection of drug resistant ... -
High CD56++CD16- natural killer (NK) cells among suboptimal immune responders after four years of suppressive antiretroviral therapy in an African adult HIV treatment cohort
Bayigga, Lois; Nabatanzi, Rose; Naluyima Sekiziyivu, Prossy; Mayanja-Kizza, Harriet; Kamya, Moses R.; Kambugu, Andrew; Olobo, Joseph; Kiragga, Agnes; Kirimunda, Sam; Joloba, Moses; Nakanjako, Damalie (BMC Immunology, 2014)Background: Up to 40% of HIV-infected individuals receiving Highly Active Antiretroviral Therapy (HAART) have poor CD4+ T-cell recovery. The role of natural killer (NK) cells in immune recovery during HAART is not well ... -
Meta-analysis to compare the accuracy of GeneXpert, MODS and the WHO 2007 algorithm for diagnosis of smear-negative pulmonary tuberculosis
Walusimbi, Simon; Bwanga, Freddie; De Costa, Ayesha; Haile, Melles; Joloba, Moses; Hoffner, Sven (BMC Infectious Diseases, 2013)Background: Smear-negative pulmonary tuberculosis (SN-PTB), which is common in HIV-infected patients, is difficult to diagnose using smear microscopy alone. In 2007, the WHO developed an algorithm to improve the diagnosis ... -
The role of speciation in positive Lowenstein-Jensen culture isolates from a high tuberculosis burden country
Worodria, William; Anderson, Julian; Cattamanchi, Adithya; Davis, J. Lucian; Boon, Saskia Den; Andama, Alfred; Yoo, Samuel D.; Joloba, Moses; Huang, Laurence; Kato-Maeda, Midori (Public Library of Science, 2011-11)Objective: To determine the need for routine speciation of positive Lowenstein-Jensen mycobacterial cultures in HIVinfected patients suspected of having pulmonary tuberculosis at Mulago Hospital in Kampala, Uganda. Methods: ... -
Selection of parasites with diminished drug susceptibility by amodiaquine-containing antimalarial regimens in Uganda.
Nawaz, Fatima; Nsobya, Samuel L.; Kiggundu, Moses; Joloba, Moses; Rosenthal, Philip J. (Oxford University Press, 2009-11-04)Background. Amodiaquine (AQ) is paired with artesunate (AS) or sulfadoxine-pyrimethamine (SP) in recommended antimalarial regimens. It is unclear how readily AQ resistance will be selected with combination chemotherapy. ...