Browsing College of Health Sciences (CHS) by Author "Walker, A. S."
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Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort
Walker, A. S.; Ssali, F.; Ford, D.; Gilks, C. F.; Reid, A.; Katabira, E.; Grosskurth, H.; Mugyenyi, P.; Hakim, J.; Darbyshire, J. H.; Gibb, D. M.; Babiker, A. G. (Elsevier, 2010-03-29)Background: Co-trimoxazole prophylaxis can reduce mortality from untreated HIV infection in Africa; whether benefits occur alongside combination antiretroviral therapy (ART) is unclear. We estimated the effect of prophylaxis ... -
Pharmacokinetics of antiretroviral drug varies with formulation in the target population of children with HIV-1
Kasirye, P.; Kendall, L.; Adkison, K. K.; Tumusiime, C.; Ssenyonga, M.; Bakeera-Kitaka, S.; Nahirya-Ntege, P.; Mhute, T.; Kekitiinwa, A.; Snowden, W.; Burger, D. M.; Gibb, D. M.; Walker, A. S. (Clinical Pharmacology & Therapeutics (Nature Publishing Group), 2012-02-21)The bioequivalence of formulations is usually evaluated in healthy adult volunteers. In our study in 19 HIV-1-infected Ugandan children (1.8–4 years of age, weight 12 to <15 kg) receiving zidovudine, lamivudine, and abacavir ...