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Prevalence of Helicobacter pylori infection during pregnancy and influence on the pregnancy anemia intervention package in Uganda among mothers at Kawempe Health Centre
(Makerere University, 2020-03)
The National Anemia Policy (2002) specifies an intervention package for anemia in pregnancy which consists of iron and folic acid supplementation, and malaria and hook worm control. However, the prevalence of anemia in ...
Role of Killer-cell Immunoglobulin-like Receptors and Human Leukocyte Antigens in Transmission and Severity of Malaria in Uganda
(Makerere University, 2021-04-08)
Background
Malaria is a life-threatening disease caused by Plasmodium falciparum. In 2018, there were an estimated 228 million cases of malaria worldwide and 405,000 malaria deaths. Malaria burden is greatly affected by ...
The impact of maternal soluble human leukocyte Antigen-G levels on risk to malaria in infants at Masafu, Busia, Uganda
(Makerere University, 2021-04-29)
Background: HLA-G is known to play a vital role in protection of the fetus in utero against maternal natural killer cells, but it is associated with progression of both viral and parasitic infection such as Plasmodium ...
Integration of DHIS2 and Climatic data for disease prediction: A case of malaria occurrence in Gulu District, Uganda
(Makerere University, 2021-01)
Background and Purpose: Prediction models are important tools that can assist public health in evidence based decision making. Since 1950, Uganda has had several prevention and control interventions but malaria is still ...
Host genetic variations and their association with malaria among Ugandan children
(Makerere University, 2021-04)
This thesis comprises studies of the relationship between host genetic factors and incidence of uncomplicated malaria in a vaccine trial site in Iganga district. The studies focused on selected host gene markers that are ...
The age-specific incidence of hospitalized paediatric malaria in Uganda
(BMC, 2020)
Background: Understanding the relationship between malaria infection risk and disease outcomes represents a fundamental component of morbidity and mortality burden estimations. Contemporary data on severe malaria risks ...
Malaria diagnosed in an urban setting strongly associated with recent overnight travel: A case–control study from Kampala, Uganda
(2020)
Malaria is frequently diagnosed in urban Kampala, despite low transmission intensity. To evaluate the association between recent travel out of Kampala and malaria, we conducted a matched case–control study. Cases were ...
The impact of integrated community case management on malaria related morbidity in children under 5 years in West Nile, Uganda
(Makerere University, 2022)
Introduction: Integrated Community case management (iCCM) provides timely and effective treatment of malaria, pneumonia, and diarrhea to children under the age of five with limited access to healthcare facilities. iCCM has ...
Extended automated NGS pipeline for reproducible analysis of mosquito genomes
(Makerere University, 2022-11)
Over the past decade, the decreasing costs of sequencing have facilitated the agnostic interrogation of vector genomes, giving access to an ever-expanding volume of high quality genomic and transcriptomic data. Today, the ...
Practical implications of a relationship between health management information system and community cohort–based malaria incidence rates
(2020)
Global malaria burden is reducing with effective control interventions, and surveillance is vital to maintain
progress. Health management information system (HMIS) data provide a powerful surveillance tool; however, its ...