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Antimalarial drug levels in biological samples: methods and applications.
(2008-09)
This thesis deals with the development and validation of analytical methods that are field-adapted and their application in the determination of antimalarial drug levels in biological samples. These methods are suitable ...
Local fever illness classifications: implications for home management of malaria strategies
(Wiley-Blackwell, 2004-11)
Background: The Ugandan Ministry of Health has adopted the WHO Home Based Fever Management strategy (HBM) to improve access to antimalarial drugs for prompt (<24 h) presumptive treatment of all fevers in children under 5 ...
Genetic polymorphisms in plasmodium falciparum associated with resistance to artemisnin combination therapy: complexity of infection during short-term culture and characterization of in-vitro sensitivity in Kampala Uganda
(2010)
Background Artemisinin-based combination therapy (ACT) is currently advocated in Africa as a means of improving treatment efficacy and slowing the development of drug resistance. However, the selection of resistant parasites, ...