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Now showing items 11-20 of 118
Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial
(BioMed Central, 2009-10-24)
Background: Malaria carries high case fatality among children with sickle cell anaemia. In Uganda, chloroquine is used for prophylaxis in these children despite unacceptably high levels of resistance. Intermittent presumptive ...
Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria in Uganda
(Public Library of Science, 2006-05)
Objectives: To compare the efficacy and safety of artemisinin combination therapies for the treatment of uncomplicated falciparum malaria in Uganda. Design: Randomized single-blind controlled trial. Setting: Tororo, Uganda, ...
Costs of setting up and maintaining home based management of fever in Kumi District
(2004)
Introduction Prompt and effective treatment of malaria in the under five year old children is essential in malaria control. Death often results from complications of malaria if treatment is not given within 24 hours. In ...
How reliable are hematological parameters in predicting uncomplicated plasmodium falciparum malaria in an Endemic Region?
(Hindawi Publishing Corporation, 2013)
Background. Malaria remains endemic in Sub-Saharan Africa. Hematological changes that occur have been suggested as potential predictors of malaria. This study was aimed at evaluating the diagnostic relevance of hematological ...
Access to health care for febrile children in Uganda: symptom recognition, care seeking practices and provider choice
(Karolinska Institutet and Makerere University, 2009)
Background: Febrile illnesses including malaria and pneumonia are leading causes of death among children under five in Uganda. Despite government efforts to increase health care access by offering free services at government ...
Complexity of plasmodium falciparum clinical samples from Uganda during short-term culture.
(University of Chicago Press, 2008-08-22)
We cultured Plasmodium falciparum parasites from 98 Ugandan children with malaria and determined the complexity of infection (COI) on the basis of msp-2 polymorphisms daily for 9 days. The mean COI decreased during culture ...
Genetic polymorphisms in plasmodium falciparum associated with resistance to artemisinin combination therapy: complexity of infection during short-term culture and characterization of in vitro sensitivity in Kampala Uganda
(Makerere University, 2010)
Background: Artemisinin-based combination therapy (ACT) is currently advocated in Africa as a means of improving treatment efficacy and slowing the development of drug resistance. However, the selection of resistant ...
Immunity to malaria
(1970)
Section I: literature is reviewed and the pattern of the development of immunity in a population exposed to high malarial endemicity is followed. This is followed by a brief discussion of specific aspects of malarial ...
Antimalarial drug levels in biological samples: methods and applications.
(2008-09)
This thesis deals with the development and validation of analytical methods that are field-adapted and their application in the determination of antimalarial drug levels in biological samples. These methods are suitable ...
Effect of HIV-1 infection on malaria treatment outcome in Uganda patients
(Makerere University Medical School, 2007)
Background: Malaria and HIV-1 infection cause significant morbidity and mortality in sub-Saharan Africa. HIV-1 increases risk for malaria with the risk increasing as immunity declines. The effect of HIV-1 infection on ...