Browsing School of Health Sciences (Health-Sciences) by Subject "Efavirenz"
Now showing items 1-2 of 2
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Non-linear mixed effects modeling of liver function biomarkers in TB-HIV patients co-treated with Rifampicin and Efavirenz based regimens
(2013-11)Introduction Survival has improved as a result of improved HIV therapy but liver disease remains a critical problem in HIV patients. HIV disease, ART and Tuberculosis treatments have all been documented to cause liver ... -
A novle polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single dose efavirenz population pharmacokinetics in Ugandans
(Wiley-Blackwell, 2009)AIMS Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim was to develop an integrated population pharmacokinetic/pharmacogenetic model and investigate the impact of genetic variations, ...