Browsing School of Health Sciences (Health-Sciences) by Type
Now showing items 1-20 of 147
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Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda
(Public Library of Science, 2008-06)Background: Uganda recently adopted artemether-lumefantrine (AL) as the recommended first-line treatment for uncomplicated malaria. However, AL has several limitations, including a twice-daily dosing regimen, recommendation ... -
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial.
(2007-05-18)Objectives: To compare the efficacy and safety of artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) for treating uncomplicated falciparum malaria in Uganda. Design: Randomized single-blinded clinical ... -
Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria in Uganda
(Public Library of Science, 2006-05)Objectives: To compare the efficacy and safety of artemisinin combination therapies for the treatment of uncomplicated falciparum malaria in Uganda. Design: Randomized single-blind controlled trial. Setting: Tororo, Uganda, ... -
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda
(Public Library of Science, 2005-07)Background Drug resistance in Plasmodium falciparum poses a major threat to malaria control. Combination antimalarial therapy including artemisinins has been advocated recently to improve efficacy and limit the spread of ... -
Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria (Review)
(Cochrane Collaboration, 2010)Background Multiple-drug-resistant malaria is widespread, and in South-East Asia resistance is high against nearly all single therapy antimalarial drugs. Here, and in other areas with low malaria transmission, the combination ... -
Assessing country-level efforts to link research to action
(World Health Organization (WHO), 2006-08)We developed a framework for assessing country-level efforts to link research to action. The framework has four elements. The first element assesses the general climate (how those who fund research, universities, researchers ... -
An assessment of Makerere University College of Health Sciences: optimizing health research capacity to meet Uganda’s priorities
(BioMed Central, 2011)Background: Health research is critical to the institutional mission of the Makerere College of Health Sciences (MakCHS). Optimizing the alignment of health research capacity at MakCHS with the health needs and priorities ... -
Assessment of the drug storage facilities and quality of generic co-formulation tablets (Stavudine, Lamivudine, Nevirapine) at HIV/AIDS treatment centers in Uganda.
(Medwell Journals, 2008)The study investigated the storage facilities and the quality of co-formulation tablets containing stavudine, lamivudine, and nevirapine at four treatment centres in Uganda. A cross-sectional survey of drug storage conditions ... -
Attitudes and perceptions about the Research and Ethics Committee in Kampala, Uganda
(Renaissance Medical Publishing, 2010)Background: The Makerere University Faculty of Medicine Research and Ethics Committee reviews and approves more than 100 new research protocols a year, yet its activities had never been evaluated as far as the researchers ... -
Azithromycin for treating uncomplicated typhoid and paratyphoid fever (enteric fever) (Review)
(John Wiley, 2008)Background Enteric fever (typhoid and paratyphoid fever) is potentially fatal. Infection with drug-resistant strains of the causative organism Salmonella enterica serovar Typhi or Paratyphi increases morbidity and mortality. ... -
Breast cancer guidelines for Uganda (2nd Edition 2007)
(Makerere University Medical School, 2008-06)Breast cancer in Uganda is the third commonest cancer in women coming only next to cancer of the cervix and Kaposi’s sarcoma. The incidence of breast cancer in Uganda has doubled from11: 100,000 in 1961 to 22:100,000 in ... -
Brighter smiles Africa - translation of a Canadian community-based Health-promoting school program to Uganda
(Taylor & Francis, 2010-08)Project goal: To adapt a successful Canadian health-promoting school initiative to a Ugandan context through international partnership. Rationale: Rural children face many health challenges worldwide; health professionals ... -
Can community health workers and caretakers recognise pneumonia in children? Experiences from Western Uganda
(Elsevier, 2006)Acute respiratory infections (ARI) are leading killers of children. Case management using community health workers (CHW) has halved ARI mortality in children in Asia. WHO/UNICEF recommend integrating pneumonia into Home ... -
Cancer of the cervix: The Uganda guidelines
(Association of Surgeons of East Africa and College of Surgeons of East, Central and Southern Africa, 2005)Cancer of the cervix (Ca Cx) is the commonest gynecological malignancy among women in Uganda contributing about 80% of all female malignancies. The incidence rate is 40:100 000. It is the leading cause of cancer related ... -
Caregivers' experience with major depression concealed by physical illness in patients recruited from Central Ugandan Primary Health Care centers
(Sage Publications, 2008)In this article, we present caregivers’ grapples with major depression seen among their physically ill patients. A thematic analysis of 29 in-depth caregiver interviews identified four themes: (a) caregivers’ perceptions ... -
Challenges faced by health workers in providing counselling services to HIV-positive children in Uganda: a descriptive study
(BioMed Central, 2010)Background: The delivery of HIV counselling and testing services for children remains an uphill task for many health workers in HIV-endemic countries, including Uganda. We conducted a descriptive study to explore the ... -
Comparison of methods in the recovery of nucleic acids from archival formalin-fixed paraffin-embedded autopsy tissues
(Elsevier, 2010-05)Archival formalin-fixed paraffin-embedded (FFPE) human tissue collections are typically in poor states of storage across the developing world. With advances in biomolecular techniques, these extraordinary and virtually ... -
Complexity of plasmodium falciparum clinical samples from Uganda during short-term culture.
(University of Chicago Press, 2008-08-22)We cultured Plasmodium falciparum parasites from 98 Ugandan children with malaria and determined the complexity of infection (COI) on the basis of msp-2 polymorphisms daily for 9 days. The mean COI decreased during culture ... -
Complexity of plasmodium falciparum infections and antimalarial drug efficacy at 7 sites in Uganda.
(University of Chicago Press, 2006-03-13)Malaria infections in Africa frequently include multiple parasite strains.We examined the relationship between the number of infecting Plasmodium falciparum strains and the responses to 3 different combination therapies ... -
Current knowledge, attitudes and practices of expectant women toward routine sonography in pregnancy at Naguru health centre, Uganda
(2009-12-01)BACKGROUND: Ultrasound has become a routine part of care for pregnant women in Uganda, being one of a range of techniques used in screening. However, it differs from most others because it allows women to view their babies. ...