Makerere University Institutional Repository: Recent submissions
Now showing items 121-140 of 14193
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Genetic analysis of sweetpotato resistance to the African sweetpotato weevils (Cylas spp.)
(Makerere University, 2024)Sweetpotato weevils (Cylas spp.) are the major pests of sweetpotatoes in Uganda and sub Saharan Africa. They cause losses ranging from 60-100% particularly during dry periods and in drought prone areas. Host plant resistance ... -
Effect of income taxation on domestic revenue growth in Uganda: an ARDL approach
(Makerere University, 2024)This study examines the effect of income taxation on domestic revenue growth in Uganda, using monthly data from July 2012 to June 2023. Employing the Autoregressive Distributed Lag (ARDL) model, the research identifies ... -
Increased prevalence of pregnancy and comparative risk of program attrition among individuals starting HIV treatment in East Africa
(PLoS ONE, 2018)Background The World Health Organization now recommends initiating all pregnant women on life-long antiretroviral therapy (ART), yet there is limited information about the characteristics and program outcomes of pregnant ... -
Midwives’ perceptions towards the Ministry of Health guidelines for the provision of immediate postpartum care in rural health facilities in Uganda
(BMC, 2023)Background Guidelines for clinical practice have been part of the Ministry of Health’s efforts to improve the quality of care for over two decades. Their benefits have been documented in Uganda. However, having practice ... -
Readiness of rural health facilities to provide immediate postpartum care in Uganda
(BMC, 2023)Background Nearly 60% of maternal and 45% of newborn deaths occur within 24 h after delivery. Immediate postpartum monitoring could avert death from preventable causes including postpartum hemorrhage, and eclampsia among ... -
Cryptococcal disease in the era of “test and treat”: Is there cause for concern?
(Oxford University Press, 2017)Treatment of cryptococcosis requires deferred initiation of antiretroviral therapy (ART). Early ART initiation may be detrimental in the context of cryptococcal infection by increasing the risk of immune reconstitution ... -
Delayed sputum culture conversion in tuberculosis human immunodeficiency virus–coinfected patients with low isoniazid and rifampicin concentrations
(Oxford Academic, 2018)Background. The relationship between concentrations of antituberculosis drugs, sputum culture conversion, and treatment outcome remains unclear. We sought to determine the association between antituberculosis drug ... -
Cellular immune activation in cerebrospinal fluid from Ugandans with cryptococcal meningitis and immune reconstitution inflammatory syndrome
(Oxford University Press, 2015)Background. Human immunodeficiency virus (HIV)-associated cryptococcal meningitis (CM) is characterized by high fungal burden and limited leukocyte trafficking to cerebrospinal fluid (CSF). The immunopathogenesis of CMimmune ... -
Correlation between co-therapy of efavirenz-based ART and pregnancy among HIV-positive women on hormonal contraceptive implants at TASO Tororo-Uganda: A retrospective review
(2018)Background: We examined the association between EFV and non-EFV based ART regimens and pregnancy outcomes among women who were on HCI in a peri-urban HIV clinic in Tororo, Uganda. Methods: We reviewed and extracted routinely ... -
Effects of HIV infection and ART on phenotype and function of circulating monocytes, natural killer, and innate lymphoid cells
(BioMed Central, 2018)HIV infection causes upregulation of markers of inflammation, immune activation and apoptosis of host adaptive, and innate immune cells particularly monocytes, natural killer (NK) and innate lymphoid cells (ILCs). Although ... -
Prevalence of lipodystrophy and metabolic abnormalities in HIV-infected African children after 3 years on first-line antiretroviral therapy
(Lippincott, 2015)Background: Most pediatric lipodystrophy data come from high-income/ middle-income countries, but most HIV-infected children live in sub-Saharan Africa, where lipodystrophy studies have predominantly investigated stavudine-based ... -
Impaired renal function and associated risk factors in newly diagnosed HIV-infected adults in Gulu Hospital, Northern Uganda
(BioMed Central, 2015)Background: Screening for renal diseases should be performed at the time of diagnosis of human immunodeficiency virus (HIV) infection. Despite the high prevalence of HIV/AIDS in Northern Uganda, little is known about the ... -
Feasibility of conducting a pilot randomized control trial of a psycho-education intervention in patients with a first episode psychosis in Uganda—A study protocol
(PLoS ONE, 2022)Background. Psychotic disorders contribute to significant morbidity and mortality partly due to the chronicity of the illness and high relapse rates. Delivering psycho-education messages about disease etiology, their signs ... -
Construction of commercial building at Plot 6 Wilson, Kampala City
(Makerere University, 2023)While Construction projects regularly involve a variety of skills that originate from the diversity professionals, specialists and suppliers, Successful implementation of a construction project can only be achieved if good ... -
The impact of refugees on the security and development of Uganda
(Makerere University, 2024)This research examined the impact of refugees on the security and development of Uganda as the largest refugee-hosting country in Africa. With nearly one million seven hundred thousand refugees, most of them are from South ... -
Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
(Elsevier, 2015)The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present ... -
Predictors and outcomes of mycobacteremia among HIV-infected smear- negative presumptive tuberculosis patients in Uganda
(BioMed Central Infectious Diseases, 2015)Background: Sputum smear microscopy for tuberculosis (TB) diagnosis lacks sensitivity in HIV-infected symptomatic patients and increases the likelihood that mycobacterial infections particularly disseminated TB will be ... -
Prevalence of infertility in cattle and associated risk factors in Kayunga District
(Makerere University, 2024)Recent publications show that the prevalence of infertility in form of perinatal calf mortality, repeat breeding and abortion has increased in some farms and an increased proportion of this loss is not associated with risk ... -
Assessment of climate sensitive indices over various reproductive phenological stages for Robusta coffee in Uganda
(Makerere University, 2024)The study aimed at developing and assessing climate-sensitive indices over the reproductive stage of Robusta coffee for both the historical (1990-2021) and future (2025-2040) periods in the Robusta Coffee Growing Region ... -
Do capital inflows boost economic growth in developing countries? the Ugandan case
(Makerere University, 2021)The main objective of this study is to assess the impact that capital inflows have on the economic growth of Uganda. A secondary analysis was conducted using the Autoregressive Distributed Lags (ARDL) regression and the ...