Browsing by Subject "Pulmonary tuberculosis"
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Assessment of diagnostic capacity of private practitioners in detection of tuberculosis in Juba City, South Sudan
(Makerere University, 2013)Introduction Tuberculosis (TB) remains a public health threat globally and is of major health concern in South Sudan. In 2012, TB notification rate for South Sudan was 88/100,000 for new cases and 96/100,000 for all ... -
Assessment of the implementation of TB/HIV collaborative activities of the south east zone in Uganda.
(2009-09)Introduction and Background: Uganda like other sub Saharan African countries is battling with a dual epidemic of TB and HIV. About 60% of TB patients are co-infected with HIV, while about 20% of HIV patients have TB ... -
Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV infected patients
(Public Library of Science, 2012-06-26)Background: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been ... -
Chest radiographic findings of pulmonary tuberculosis in severely immunocompromised patients with the human immunodeficiency virus
(The British Institute of Radiology, 2012-06)Objective: We describe chest radiograph (CXR) findings in a population with a high prevalence of human immunodeficiency virus (HIV) and tuberculosis (TB) in order to identify radiological features associated with TB; to ... -
Clinical spectrum, risk factors and outcome of immune reconstitution inflammatory syndrome in patients with tuberculosis-HIV coinfection
(International Medical Press, 2012)BACKGROUND: Here, we aimed to determine the clinical spectrum, predictors and outcomes of paradoxical tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) in a resource-limited setting. METHODS: In a ... -
A comparison of sodium hypochlorite n-acetyl-l-cystein sputum concentration methods and culture for diagnosis of smear negative pulmonary tuberculosis suspects attending Mulago hospital.
(2005)The sensitivity of direct sputum smear microscopy is very low, ranging from 25 to 65%. It is thus inevitable that direct smear microscopy needs to be improved or other methods of diagnosis of smear negative (TB) be designed. ... -
Diagnostic accuracy of the genexpert system among children with pulmonary tuberculosis at Mulago Hospital
(Makerere University, 2012)Background: The GeneXpert system is a rapid mycobacteria tuberculosis diagnostic tool which has shown higher sensitivity and was validated for use in children based on successful data among the adult population. This ... -
Health service delay and associated factors among pulmonary tuberculosis patients presenting to Mulago Hospital: a cross sectional study.
(2009-10)Delay in the diagnosis of pulmonary tuberculosis (PTB) is common in many countries in sub-Saharan Africa. Timely diagnosis of active TB is particularly crucial to minimise not only morbidity and mortality in the community, ... -
Incremental yield of serial sputum cultures for diagnosis of tuberculosis among HIV infected smear negative pulmonary TB suspects in Kampala, Uganda
(PLoS ONE, 2012-05-22)Background: Sputum culture is the gold standard for diagnosis of pulmonary tuberculosis (PTB). Although mostly used for research, culture is recommended by the World Health Organization for TB diagnosis among HIV infected ... -
The past and present radiographic manifestations of pulmonary tuberculosis at Mulago Hospital
(1989-04)A cross-sectional study of the chest radiographs of adult tuberculosis patients, seen at Mulago Hospital, in 1972, 1979 and 1988 was carried out between August and December 1988. The aim of the study was to determine the ... -
Patient and health service delay in pulmonary tuberculosis patients attending a refferal hospital: a cross sectional study
(BMC Public Health, 2005)Background: Delays in diagnosis and initiation of effective treatment increase morbidity and mortality from tuberculosis as well as the risk of transmission in the community. The aim of this study was to determine the time ... -
Predictors of treatment failure among patients with smear positive pulmonary tuberculosis in the Tuberculosis Clinic in Mulago Hospital: a case control study
(2009-09-22)Background: Treatment failure is a threat to the control of tuberculosis (TB) because of its association with Multi Drug Resistant tuberculosis (MDR TB) and also because affected patients continue to spread TB. Patients ... -
The prevalence and factors associated with adrenal insufficiency among patients with sputum smear positive pulmonary tuberculosis admitted to Mulago Hospital
(2009-09)Background: Tuberculosis (TB) is still one of the common infections which cause adrenal insufficiency in the developing countries. That is why we set out to determine the prevalence and factors associated with adrenal ... -
The prevalence and factors associated with adrenal insufficiency among patients with sputum smear positive pulmonary tuberculosis admitted to Mulago Hospital.
(2009-09)BACKGROUND: Tuberculosis (TB) is still one of the common infections which cause adrenal insufficiency in the developing countries. That is why we set out to determine the prevalence and factors associated with adrenal ... -
Prevalence and factors associated with pulmonary tuberculosis among adults in fishing communities of Lake Victoria, Uganda.
(Makerere University, 2012-06)Background: Although TB is both a treatable and immunizable disease, it still causes a lot of morbidity and mortality globally, and particularly in the developing world. With a national TB incidence of 330 cases of all ... -
Prevalence and factors associated with pulmonary tuberculosis among children aged 2 to 59 months presenting with severe pneumonia at Alsabah Children’s Hospital, Juba, South Sudan
(Makerere University, 2019-09)Background: Tuberculosis (TB) is a major public health problem at a global level. According to the World Health Organization (WHO) in 2018, approximately 10 million people developed TB in 2017, of which 1.0 million (10%) ... -
Prevalence and factors associated with pulmonary tuberculosis in children admitted with severe pneumonia in Mulago Hospital
(Makerere University, 2012)Introduction: Tuberculosis is a major cause of morbidity and mortality in children with severe pneumonia. A study done in Uganda by Bakeera et al in 2001 found 2% TB in children with severe pneumonia, while a similar study ... -
The role of speciation in positive Lowenstein-Jensen culture isolates from a high tuberculosis burden country
(Public Library of Science, 2011-11)Objective: To determine the need for routine speciation of positive Lowenstein-Jensen mycobacterial cultures in HIVinfected patients suspected of having pulmonary tuberculosis at Mulago Hospital in Kampala, Uganda. Methods: ... -
Time to sputum culture conversion and associated factors among drug resistant tuberculosis patients treated with Bedaquiline at Mulago Hospital, Uganda
(Makerere University, 2024)Introduction: Sputum culture conversion in patients with pulmonary tuberculosis (PTB) is considered the most important interim indicator of the effectiveness of anti-TB treatment for drug resistant disease. Bedaquiline ... -
Urban movement and alcohol intake strongly predict defaulting from tuberculosis treatment: an operational study
(Public Library of Science, 2012-05-02)Background:High levels of defaulting from treatment challenge tuberculosis control in many African cities. We assessed defaulting from tuberculosis treatment in an African urban setting. Methods: An observational study ...