Browsing Infectious Diseases Institute (IDI) by Author "Manabe, Yukari C."
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An Autopsy Study Describing Causes of Death and Comparing Clinico-Pathological Findings among Hospitalized Patients in Kampala, Uganda
Cox, Janneke A.; Lukande, Robert L.; Nelson, Ann M.; Mayanja-Kizza, Harriet; Colebunders, Robert; Van Marck, Eric; Manabe, Yukari C. (PLoS ONE, 2012-03-14)Background: Information on causes of death in HIV-infected patients in Sub-Saharan Africa is mainly derived from observational cohort and verbal autopsy studies. Autopsy is the gold standard to ascertain cause of death. ... -
Developing independent investigators for clinical research relevant for Africa
Manabe, Yukari C.; Katabira, Elly; Brough, Richard L.; Coutinho, Alex G.; Sewankambo, Nelson; Merry, Concepta (BioMed Central, 2012)Sustainable research capacity building requires training individuals at multiple levels within a supportive institutional infrastructure to develop a critical mass of independent researchers. At many African medical ... -
Evaluation of portable point-of-care CD4 counter with high sensitivity for detecting patients eligible for antiretroviral therapy
Manabe, Yukari C.; Wang, Yaping; Elbireer, Ali; Auerbach, Brandon; Castelnuovo, Barbara (Public Library of Science, 2012-04-19)Background: Accurate, inexpensive point-of-care CD4+ T cell testing technologies are needed that can deliver CD4+ T cell results at lower level health centers or community outreach voluntary counseling and testing. We ... -
In reply to `Empirical tuberculosis treatment or improved diagnostics?'
Manabe, Yukari C.; Worodria, William; Cobelens, Frank (International Union Against Tuberculosis and Lung Disease, 2012-02-16)We read the article by Lawn and colleagues with great interest. Atypical presentation and limited diagnostic capability in resource-limited settings lead to delays in treatment that could contribute to high rates of ... -
Integration of HIV and TB services results in improved TB treatment outcomes and earlier prioritized ART initiation in a large urban HIV clinic in Uganda
Hermans, Sabine M.; Castelnuovo, Barbara; Katabira, Catherine; Mbidde, Peter; Lange, Joep M. A.; Hoepelman, Andy I. M.; Coutinho, Alex; Manabe, Yukari C. (Lippincott, Williams & Wilkins, 2012-06-01)Background: The World Health Organization recommends that treatment of tuberculosis ... -
Rifampicin for continuation phase tuberculosis treatment in Uganda: a cost-effectiveness analysis
Manabe, Yukari C.; Hermans, Sabine M.; Lamorde, Mohammed; Castelnuovo, Barbara; Mullins, C. Daniel; Kuznik, Andreas (Public Library of Science, 2012-06)Background: In Uganda, isoniazid plus ethambutol is used for 6 months (6HE) during the continuation treatment phase of new tuberculosis (TB) cases. However, the World Health Organization (WHO) recommends using isoniazid ... -
Sub-optimal vitamin B-12 levels among ART-Naïve HIV positive individuals in an urban cohort in Uganda
Semeere, Aggrey S.; Nakanjako, Damalie; Ddungu, Henry; Kambugu, Andrew; Manabe, Yukari C.; Colebunders, Robert (Public Library of Science, 2012-07-02)Malnutrition is common among HIV-infected individuals and is often accompanied by low serum levels of micronutrients. Vitamin B-12 deficiency has been associated with various factors including faster HIV disease progression ...