College of Health Sciences (CHS)
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Factors associated with virological non-suppression among adult HIV clients with low-level viremia in Kampala, Uganda
(Makerere University, 2022)The goal of antiretroviral therapy is to maximize the inhibition of infectious virion production to below the level of detection of less than 50 copies/ml. Clients with LLV have not been fully studied in Uganda and ... -
Effect of perioperative blood transfusion on complications following emergency non-trauma laparotomy: A prospective cohort study
(Makerere University, 2024)Introduction: Blood transfusion may be required in the management of patients undergoing emergency non-trauma laparotomy. However, retrospective cohort studies involving patients undergoing emergency laparotomy have ... -
Evaluating readiness for implementation of the eight antenatal care contacts as per the World Health Organization guidelines in Bukwo District, Uganda
(Makerere University, 2023)Background: Low and Middle Income Countries (LMICs) account for around 99 % of maternal deaths worldwide, with Sub-Saharan Africa (SSA) responsible for about 66 % of these demises. The new Antenatal Care (ANC) model with ... -
A machine learning approach to predict E. coli antibacterial resistance using whole-genome sequencing data
(Makerere University, 2023)Background: Antimicrobial resistance (AMR) is a significant global health threat, particularly impacting low- and middle-income countries(LMICS) such as Uganda, where reliable and rapid methods for detecting AMR in E. coli ... -
Uptake of preventive nutrition interventions among caretakers of children under 5 years in a pastoral setting of South Sudan: A case of Kapoeta South County
(Makerere University, 2023)Background: Preventive nutrition interventions are usually implemented without understanding how multiple factors affect uptake. Pastoralist populations have shown low uptake. A multidimensional study of uptake in the ... -
Health related quality of life and associated factors of post-pulmonary tuberculosis lung disease patients treated from Mulago National Referral Hospital, Kampala - Uganda
(Makerere University, 2024)Introduction: By the end of 2020, there were approximately 155 million TB survivors globally. TB survivors have up to three times increased risk of mortality from post-Pulmonary TB lung complications compared with the ... -
Exploring the under reporting of pregnancy and adverse pregnancy outcomes in population and health surveys : a multi-country qualitative study
(Makerere University, 2023)Introduction: Globally in 2021, an estimated 2.3 million newborn deaths and 1.9 million stillbirths occurred, with highest mortality in sub-Saharan Africa and southern Asia. True mortality is likely higher due to under ... -
Transcriptome analysis of micro-RNAs associated with COVID-19 disease
(Makerere University, 2023-11)The host microRNA (miRNA), which is essential for maintaining the epithelial cell barrier in the respiratory tract as well as controlling viral entry and reproduction, plays a significant role in COVID-19 infection. ... -
Knowledge attitudes and practices towards premarital medical examination among young unmarried people aged 18-49 years in Lyantonde District, Uganda
(Makerere University, 2024)Introduction: Undergoing Premarital Medical Examination (PME) helps couples to ascertain the compatibility of their health status and the likelihood of producing healthy offspring prior to their marriage decisions. This ... -
Examining the gaps and barriers in monitoring and evaluation of male engagement in family planning among selected Non-governmental organizations in the health sector in Kampala Capital City Authority, Uganda
(Makerere University, 2023)Male engagement in reproductive health/family planning is considered an integral component in maximizing reproductive health outcomes. However, monitoring and evaluation efforts towards this approach is significantly low, ... -
Factors associated with infant and young child feeding practices among mothers of children 0-23 months attending Banadir Hospital in Wadajir District, Somalia
(Makerere University, 2023)Understanding the prevailing feeding practices of infants and young children is crucial for implementing or improving health and nutrition programs in a country. In Somalia, the prevalence of Malnutrition is high. The ... -
Evaluation of the efficacy of fresh Saccharum officinarum linn goa (var) stem juice against aspirin-induced ulcers in wistar albino rats.
(Makerere University, 2023-08)Back ground: In Uganda, 12% to 25% of the population is living with peptic ulcer disease. Efforts to treat the disease have become much more difficult due to rising prevalence of drug resistance, unbearable adverse drug ... -
Characterization of performance of three commercial monoclonal antibodies in detection of spike protein in SARS-CoV-2
(Makerere University, 2024)The study aimed at characterizing the Performance of three commercial monoclonal antibodies in detection of spike protein in SARS-CoV-2. This was looking at avidity and specificity of the monoclonal antibodies which would ... -
Prevalence of gene xpert mtb trace detected result and health workers’ perspectives on diagnosis and management at five health facilities in uganda
(Makerere University, 2023-11-30)Background: Xpert MTB/RIF Ultra is a cartridge-based rapid molecular assay, introduced in 2017 as an updated version of the Xpert MTB/RIF for tuberculosis (TB) diagnosis. Gene Xpert Ultra has sensitivity (88%) nearing that ... -
Prevalence and factors associated with suicidality among the elderly attending non-psychiatric wards at Mulago National Referral Hospital and Uganda Cancer Institute
(Makerere University, 2023-09-11)Background: The elderly are especially vulnerable to suicide. Older adults are at a substantially higher risk of dying by suicide compared to the younger age categories for a number of reasons including the fact that they ... -
Effect of family health groups on nutritional status of children 6-59 months in Kabale and Rukiga Districts in Southwestern Uganda
(Makerere University, 2023)Background: Family Health Groups (FHGs), an intervention to address malnutrition was operationalized in 2016 to help pregnant and lactating mothers adopt behaviors consistent with good nutritional and health practices. ... -
Effects of locally made double – layered cloth face masks on exercise performance and cardiopulmonary parameters during physical activity in healthy adults
(Makerere University, 2023)Background: Due to the COVID–19 pandemic, cloth facemasks are used worldwide as a major prevention method against the spread of the disease, keeping dust away from the respiratory tract and avoiding acquiring other respiratory ... -
Reported adverse drug reactions of antiretroviral therapy generic formulations in Uganda
(Makerere Univesrity, 2023)Background: Generic Antiretroviral drugs are commonly used in the developing countries and this has greatly contributed to the scaling up of ART. Generics vary in formulation including excipients, the production conditions ... -
Exploring clinical ethics consultation experiences at Uganda Cancer Institute: version 11
(Makerere University, 2023-11)Background: Globally, healthcare providers (HCPs), hospital administrators, as well as patients and their caretakers are increasingly being confronted with complex moral, social, cultural, ethical and legal dilemmas during ... -
A model to predict the correct stocking levels of artemisinin-based combination therapies in Kira Health Center III and Kisenyi Health Centre IV
(Makerere University, 2023)Introduction The persistent low stock/stock-outs of malaria essential medicines, such as, Artemisinin-based Combination Therapies (ACTs), in public health facilities is a major hinderance to treatment and management of ...