Ojara, Williams Francis(Makerere University, 2014-10)
Cyclophosphamide is one of the most widely used anticancer drugs. It forms part of various combinations used in treating a range of solid and hematologic tumours in both children and adults in Uganda. It is part of the ...
Background: Mycobacterium tuberculosis (MTB), the causative agent of tuberculosis (TB) infects over 2 billion people world-wide with the vast majority of deaths from TB in the developing world. Strains of MTB vary in ...
ABSTRACT
Introduction: Non-Communicable Diseases including hypertension are increasingly becoming common among HIV-infected patients in chronic care. HIV-infected women who also become pregnant are at increased risk of ...
Introduction:
Maternal mortality ratio for Uganda has remained high despite the different measures to prevent maternal mortality. Uterine rupture remains one of the main direct causes of maternal and perinatal mortality ...
Background: Carbapenemases have increasingly been reported in Enterobacteriaceae worldwide.Chromosomal and plasmid mediated resistance in Enterobateriaceae, renders them the most variable of all bacteria in susceptibility ...
Introduction: Tuberculosis (TB) is a major public health concern worldwide, with more than 2 billion people with latent infection. The precise identification of bacterial pathogens at the strain level is essential for ...
Kasule, Umar Uthuman(Makerere University, 2015-08)
Introduction
Allergic rhinitis is the most common allergic respiratory disorder globally. It constitutes a public health problem with a prevalence of 10% - 40%. The trend is increasing, affecting 19% of the general ...
Background: The introduction of GeneXpert in the diagnostic algorithm of TB was envisaged to cause improvements in the diagnosis. Although some factors that influence its performance including HIV status, sputum volume ...
Background
Completion of graduate education is evidenced at most academic institutions as submission of the final dissertation. Many students progress successfully in their course works, tests and written examinations. ...
Background: Candida species are one of the causers of lower genital tract infections of women. Although Candida albicans is the commonest, other species have emerged yet they are less susceptible to azole antifungals and ...
INTRODUCTION: Private medical clinics play an important role in the delivery of health services in Uganda and account for 46% of all the health care facilities in Uganda. They are usually the first place where almost half ...
Introduction: Cervical spine dislocations are serious injuries that are a major cause of morbidity and mortality. In well resourced centers cervical spine dislocations are reduced by rapid traction with the use of increasing ...
Background:
Diabetes mellitus is common and on the increase globally. The associated accelerated macro-vascular angiopathy impairs blood flow in medium sized arteries including hand collateral arteries among others with ...
Bimenya, Gabriel; Okot, Julius; Othieno, Emmanuel; Lynnette, T Kyokunda; Ibingira, Charles; Okwi, L Andrew(2016-04)
Background: Magnesium is the second most abundant intracellular cation, with only a small proportion of the body’s content being in the extracellular fluid. It is required for the active transport of other cations such as ...
Introduction: Bacteremia is associated with significant morbidity and mortality in the developing world. In Uganda, antibiotic susceptibility testing is not routinely done among patients suspected to have sepsis. This ...
Background
Half of the world’s population is at the risk of malaria and an estimated 243million cases led to nearly 830,000 deaths in 2008, with most of the cases and death found in Africa. The morbidity and mortality ...
Background
In Sub-Saharan Africa where Uganda lies, half of the population lacks reliable access to essential medicines and out of pocket expenditure by patients is as high as 34%. Generic drug substitution, if implemented ...
Background: In Uganda, Tenofovir-based regimen is recommended as first line particularly for HIV/AIDS adult and adolescent patient and for option B+ in prevention of mother-to-child transmission (PMTCT). As a result of ...
Background: Majority of HIV-infected individuals who start HAART at CD4 counts <200 cells/µl show a marked CD4+T-cell increase to absolute CD4 counts above 500 cells/µl. The CD4+ T-cell count is the main measure for immune ...
Background: Trauma is the leading cause of death in the developed world. Accurate assessment of severity of
injuries is critical in informing treatment choices. Current models of assessing severity of injury are not ...