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Rhomboids of mycobacteria: insight from phylogeny, genomic and complementation analysis.
(Makerere University, 2014)
Background
The rhomboid superfamily of proteins includes novel trans-membrane Serine-proteases that occur in all life-kingdoms, and are responsible for vital roles such as signaling in Drosophila, red blood cell invasion ...
Evaluation of capilia TB assay for rapid identification of mycobacterium tuberculosis complex in BACTEC MGIT 960 and BACTEC 9120 blood cultures
(BioMed Central, 2012)
Background: Capilia TB is a simple immunochromatographic assay based on the detection of MPB64 antigen specifically secreted by the Mycobacterium tuberculosis complex (MTC). Capilia TB was evaluated for rapid identification ...
Factors associated with health seeking behaviour of pulmonary tuberculosis patients at Mulago National Referral Tuberculosis Treatment Centre.
(2002-06)
SETTING:
The study was carried out at Mulago National Referral Tuberculosis Treatment Centre, Kampala, Uganda, East Africa.
OBJECTIVE:
The study aimed at assessing factors associated with the health-seeking behavior of ...
Strain diversity of mycobacterium tuberculosis non-Uganda isolates from patients with pulmonary tuberculosis in Kawempe
(Makerere University, 2013-05)
Background: Tuberculosis is a major public health problem in peri-urban areas of Kampala and Uganda in general. To date there is inconclusive information about strain diversity of Mycobacterium tuberculosis of the non ...
Performance of the tuberculosis specimen referral system in the South Western TB zone of Uganda
(Makerere University, 2017-02)
Background: Multidrug resistant tuberculosis (MDR-TB) stands at 12.5% in Uganda among the retreatment TB cases. In an effort to accelerate the WHO-recommended MDR-TB diagnosis and surveillance, the Uganda NTLP in 2008 ...
Compensatory mutations in rpoA, rpoC and rpoD genes among rifampicin-resistant Mycobacterium tuberculosis isolates from Uganda
(Makerere University, 2019-11-11)
Background; Mycobacterium tuberculosis can acquire resistance to rifampicin through mutations in the rpoB gene. This is normally accompanied by the fitness cost which however can be mitigated by the acquired secondary ...