College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 3115
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Deciphering Rifampicin resistance among Tuberculosis patients who have trace and indeterminate results on Xpert MTB/RIF ultra assay
(Makerere University, 2024-10-22)Although WHO endorsed the GeneXpert test as the first initial test for Tuberculosis diagnosis, some of the GeneXpert Ultra results include MTB detected trace, RIF resistance indeterminate which necessitates a sample rerun, ... -
Evidence of molecular adaptive evolution of SARS-CoV-2 in Uganda using whole genome sequences
(Makerere University, 2024-10)Background: Seasonal influenza and coronaviruses both exhibit continual adaptive evolution during endemic circulation in the human population. The rapid evolution of human pathogenic RNA viruses can undermine the efforts ... -
Selected bacterial etiology of acute diarrhea in under five children at Mulago National Referral Hospital Kampala, Uganda.
(Makerere University, 2024-10)Background: Diarrhea is understood as the passing of three or more passages of loose or watery stools per day according to WHO and is considered among the major causes of childhood mortality and morbidity. Diarrhea kills ... -
Perinatal death in northern Uganda: risk factors, associated postpartum depression, lived experiences and the cultural perspective
(Makerere University, 2024-11)Uganda’s institutional perinatal mortality estimated at 17.8 deaths per 1,000 births (FY 2022/2023), is associated with negative emotional and psychosocial outcomes among families. However, it has received insufficient ... -
Anti mülleran hormone levels and associated factors among adult females in Kampala
(Makerere University, 2024-11)Anti Mülleran Hormone (AMH), a type of glycoprotein, is found in both men and women. It is produced exclusively in the gonads and is involved in the regulation of follicular growth and development. AMH has over the years ... -
Factors associated with health literacy in sexual and reproductive health: a cross-sectional study among south Sudanese refugee women in Rhino camp refugee settlement, West Nile, Uganda
(Makerere University, 2024)Introduction: Refugee women in Uganda experience poorer sexual and reproductive health (SRH) outcomes than women in the host community. Previous studies have shown that refugee women face several significant barriers to ... -
Adapting and evaluating a mindfulness and acceptance-based intervention supporting mental health and adherence to anti-retroviral therapy among older adolescents in Kampala
(Makerere University, 2023-01-23)Background Adolescents living with HIV in sub-Saharan Africa have a higher mental health burden, lower care engagement, and poor medication adherence. To improve treatment outcomes, support interventions that are tailored ... -
Study participants preferences for dissemination methods of health research findings at Makerere University, College of Health Sciences
(Makerere University, 2022)Background: Health research findings if not disseminated effectively may negatively impact the lives of the research community. While it is an ethical obligation of researchers to disseminate health research results to ... -
Treatment success and associated factors among Tuberculosis patients identified and linked to care using Mobile Chest X-Ray In East and Central Uganda.
(Makerere University, 2024-10)Introduction: Active case-finding (ACF) is an important component in fighting TB and is being piloted in several districts using mobile TB clinics equipped with Xray units. However, there is still limited information on ... -
Short-term outcomes of non-operatively managed Diaphyseal Clavicle fractures in adults at Mulago National Referral Hospital.
(Makerere University, 2024-10-17)Introduction: Clavicular fractures constitute around 4% of all fractures globally, majority (80%) of these occurring in the diaphyseal region (Kihlström, Möller et al., 2017). At Mulago National Referral Hospital (MNRH), ... -
Spinal drainage output and associated factors of improvised versus standard surgical drains among postoperative patients at Mulago Hospital : a comparative study
(Makerere University, 2024)Introduction: Surgical drains play a vital role in preventing fluid accumulation in patients who undergo surgery. The scarcity and cost challenges of standard surgical drains lead healthcare workers to employ improvised ... -
Prevalence and patterns of metastatic tumors to the spine among adult patients at Mulago National Referral Hospital and Uganda Cancer Institute
(Makerere University, 2024)Introduction: Metastatic tumors to the spine pose significant clinical challenges and represent a common complication in advanced cancer patients. At least 30% to 70% of cancer patients may experience metastasis to the ... -
Prevalence, associated risk factors, and consequences of medication errors in poultry practice in Wakiso district
(Makerere University, 2024)Medication errors are a serious health challenge in both humans and animals including in poultry practice in Uganda. However, limited information exists on the extent of burden of medication errors, risk factors and its ... -
Understanding genetic diversity and rapid drug resistance prediction in mycobacterium tuberculosis from whole-genome sequence and other epidemiological data
(Makerere University, 2024-06)Tuberculosis (TB) remains one of the major global health problems with an estimated 1.6 million deaths worldwide. The availability of whole-genome sequence (WGS) data offers a good avenue for understanding genetic diversity ... -
Sedation practices and 28 day clinical outcomes among mechanically ventilated adult patients in Uganda's ICUs : a prospective longitudinal multicentre study
(Makerere University, 2024)Introduction: Sedation is a common intervention among mechanically ventilated patients in the Intensive care units (ICUs) to facilitate anxiolysis, improve ventilator synchrony, and prevent agitation. Its use has been ... -
Prevalence and factors associated with smell disorders among patients with Type 2 Diabetes mellitus at Mulago National Referral Hospital
(Makerere University, 2024)Background: Diabetes mellitus continues to present a pressing global challenge, affecting an estimated 537 million adults worldwide, a figure expected to increase to 643 million by 2030. Smell disorders like anosmia and ... -
Prevalence and factors associated with Premenstrual Dysphoric Disorder among female students attending Mulago School of Nursing and Midwifery.
(Makerere University, 2024)Background: Premenstrual Dysphoric Disorder (PMDD) is a severe mood disorder impacting a substantial number of women in their reproductive age. Despite a global prevalence of 3-8%, PMDD remains poorly understood, particularly ... -
Antinociceptive activity and acute toxicity profile of Leucus calostachys olive in animal models
(Makerere university, 2024-11)Pain remains a cardinal sign and symptom for most diseases and a major reason for patients visiting healthcare providers. Conventional treatment modalities do not adequately address pain, and as a result, most local ... -
Diagnostic reference levels for adult computed tomography examinations in Uganda
(Makerere University, 2023)Background: Computed tomography (CT) is a critical tool in medicine. Although CT is associated with higher radiation doses compared with planar radiographic imaging, it is often the most appropriate modality and first line ... -
Evaluation of hypoglycemic activity, phytochemical composition and acute toxicity of Opuntia humifusa Raf. cladode extracts in Wistar albino rats
(Makerere University, 2024-10-29)Background Local communities in Central Uganda are using the cladodes of Opuntia humifusa in the treatment of diabetes mellitus with the claim that the plant is effective. However, efficacy and safety of the plant is not ...