College of Health Sciences (CHS): Recent submissions
Now showing items 21-40 of 3366
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Castelnuovo, B. et al. (2018). Antiretroviral treatment Long-Term (ALT) cohort: a prospective cohort of 10 years of ART-experienced patients in Uganda
(BMJ, 2018)Purpose Little information is available on patients on antiretroviral treatment (ART) after a long-term period from sub-Saharan Africa, with the longest follow-up and related outcomes being after 10 years on ART. At the ... -
A Prospective Evaluation of a multisite Cryptococcal Screening and Treatment program in HIV clinics in Uganda
(Lippincott, 2018)Background—Cryptococcus is a leading cause of AIDS-related mortality. Cryptococcal antigen (CrAg) is detectable in blood before meningitis onset, and predicts death. CrAg screening amongst those with advanced HIV, and ... -
Adolescent pregnancy at antiretroviral therapy (ART) initiation: a critical barrier to retention on ART
(Wiley Online Library, 2018)Introduction: Adolescence and pregnancy are potential risk factors for loss to follow-up (LTFU) while on antiretroviral therapy (ART). We compared adolescent and adult LTFU after ART initiation to quantify the impact of ... -
Issues with measuring hepatitis prevalence in resource-limited settings
(Elsevier, 2018) -
Molecular tests expedite the diagnosis of multidrug-resistant tuberculosis in childhood
(Academia.edu, 2018)The diagnosis of paediatric tuberculosis (TB) is difficult, partly due to the low accuracy of traditional tests. Molecular TB tests can diagnose presumptive TB and drug-resistant TB (DR-TB) rapidly and may guide crucial ... -
Risk factors for and types of oesophageal cancer
(The Lancet, 2004) -
Characteristics and outcomes of admitted patients infected with SARS-CoV-2 in Uganda
(BMJ, 2020)Rationale: Detailed data on the characteristics and outcomes of patients with COVID-19 in sub-Saharan Africa are limited. Objective: We determined the clinical characteristics and treatment outcomes of patients diagnosed ... -
Metabolic syndrome and 10-year cardiovascular risk among HIV-positive and HIV-negative adults: A cross-sectional study
(Wolters Kluwer, 2020)To determine the prevalence and correlates of metabolic syndrome (MetS) and compare 10-year cardiovascular disease (CVD) risk among Kenyan adults with and without HIV infection.We conducted a cross-sectional study among ... -
Intimate partner violence and self-reported pre-exposure prophylaxis interruptions among HIV-negative partners in HIV serodiscordant couples in Kenya and Uganda
(Lippincott, 2018)Background: Oral pre-exposure prophylaxis (PrEP) is effective for HIV prevention, and PrEP delivery studies are investigating ways to deliver PrEP with high adherence. However, in many settings with high HIV burden, intimate ... -
Tuberculosis preventive therapy (TPT) to prevent tuberculosis co-infection among adults with HIV-associated cryptococcal meningitis: A clinician's perspective
(Elsevier, 2020)As part of the END TB strategy, the World Health organization (WHO) recommends provision of tuberculosis preventive therapy (TPT) to all people at high risk of developing active TB disease. Patients with HIV-associated ... -
Prevalence and nature of potential drug-drug interactions among hospitalized HIV patients presenting with suspected meningitis in Uganda
(BMC, 2020)Background: Management of co-infections including cryptococcal meningitis, tuberculosis and other opportunistic infections in persons living with HIV can lead to complex polypharmacotherapy and increased susceptibility to ... -
Prevalence and associated factors of erectile dysfunction among men attending the urology clinic at Mulago Hospital: a cross-sectional study
(Makerere University, 2025)Background: Erectile dysfunction (ED) is a significant public health concern affecting men’s quality of life and relationships. Despite its global burden, epidemiological data on ED in Uganda, particularly among men seeking ... -
Prevalence and factors associated with Hypovitaminosis D among patients with colorectal cancer in Mulago National Referral Hospital and Uganda Cancer Institute (Uganda): A cross-sectional study
(Makerere University, 2025)Introduction: The burden of colorectal cancer has increased in Uganda. Vitamin D has immunomodulatory effects that are not only protective against malignancies such as colorectal cancer but are also associated with reduced ... -
Prevalence and factors associated with shunt survival among hydrocephalus patients that underwent ventriculoperitoneal shunt surgery at Mulago National Referral Hospital: a retrospective cross-sectional study
(Makerere university, 2025-05)Introduction: Ventriculoperitoneal shunt (VPS) surgery is one of the mainstay treatments for hydrocephalus patients. Some patients that undergo ventriculoperitoneal shunt surgery experience eventful survival. However, ... -
Prevalence of needlestick injuries and factors associated with access of PEP among health workers at casualty Mulago National Referral Hospital-a cross sectional study
(Makerere University, 2025)Background: Needle stick injuries (NSI) are accidental skin-penetrating puncture wounds from a hollow- bore needle containing another person's blood or body fluid. They are a very prevalent challenge among health workers ... -
Prevalence and factors associated with clinical outcomes among patients hospitalized with chronic obstructive lung disease on the pulmonology wards at Kiruddu and Mulago National Referral Hospital.
(Makerere University, 2024)Background: COPD is a chronic airway disease condition currently on the rise in many low middle-income countries (LMICs). This is attributed to poorly treated TB, asthma, cigarette smoking and air pollution among others. ... -
Predictors of mortality among severe traumatic brain injury patients admitted at Mulago Hospital. A retrospective cross-sectional study
(Makerere University, 2025)Introduction Severe traumatic brain injury (STBI) contributes significantly to death and disability especially in low and middle income countries. However, little is known about the mortality rate and its predictors ... -
Knowledge, attitudes and practices regarding infection prevention and control among non-medical handlers of healthcare waste in public healthcare facilities in Wakiso district.
(2024-11-13)Background: Healthcare waste can result in exposure to infectious conditions. Therefore, medical waste handlers need to adhere to infection prevention and control. Waste handlers, especially the non-medical ones, play a ... -
Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner
(PNAS, 2022)HLA class I (HLA-I) allotypes vary widely in their dependence on tapasin (TAPBP), an integral component of the peptide-loading complex, to present peptides on the cell surface. We identified two single-nucleotide polymorphisms ... -
Sticks and wheelchairs for elderly people in central Uganda: values of utility, provenance and presentation
(Cambridge University Press, 2022)While mobility-assistive devices ease movement and independence of persons with disabilities, their use may depend on their social and symbolic meaning. This article departs from our observation that elderly people in ...