College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 3366
-
Dyslipidaemias in women using hormonal contraceptives: a cross sectional study in Mulago Hospital Family Planning Clinic, Kampala, Uganda
(BMJ, 2018)Objective To determine the prevalence and factors associated with dyslipidaemias in women using hormonal contraceptives. Design Cross-sectional study. Setting Mulago Hospital, Kampala, Uganda Participants Three hundred ... -
Overcoming challenges of managing chronic obstructive pulmonary disease in low-and middle-income countries
(Taylor and Francis, 2024)Introduction: Chronic obstructive pulmonary disease (COPD) ranks among the top three global causes of death, with 90% of fatalities concentrated in low- and middle-income countries (LMICs). The projected rise in COPD burden, ... -
Prevalence of perceived occupational injuries and associated factors among factory workers in Mogadishu, Somalia
(Makerere University, 2024)Introduction: Occupational injuries are a significant public health concern, particularly in developing countries where the burden is 10 to 20 times higher than in industrialized nations. In Somalia, factory work is ... -
Prevalence of chronic kidney disease among young people living with HIV in Sub Saharan Africa: A systematic review and meta-analysis
(PLoS ONE, 2024)Background Globally, the prevalence of chronic kidney disease (CKD) is increasing among young people living with HIV (YPLHIV), with inconsistent estimates. Aggregated data on the prevalence of CKD are needed in sub-Saharan ... -
Comparison of the prevalence and associated factors of chronic kidney disease diagnosed by serum creatinine or cystatin C among young people living with HIV in Uganda
(BMC, 2024)Introduction Young people living with HIV (YPLHIV) are at increased risk of developing chronic kidney disease (CKD) which is associated with high mortality and morbidity. Early diagnosis is important to halt progression. ... -
Sex differences in the prevalence of geriatric syndromes among older people living with HIV attending an urban outpatient clinic in Kampala, Uganda
(Dovepress, 2024)Background Older people living with HIV (PLHIV) are at high risk of developing geriatric syndromes. Data on geriatric syndromes among older PLHIV in sub-Saharan Africa are scarce. We examined sex differences in the ... -
Feasibility and factors affecting the diagnostic accuracy of a self-administered PHQ-9 for depression screening at Mukono Church of Uganda Hospital HIV Clinic
(Makerere University, 2025)Background: Comorbid depression is three times more prevalent among people living with HIV in Uganda, yet its diagnosis is still a challenge due to multiple factors such as inadequate health care work force that results ... -
The prevalence and factors associated with depression among undergraduates at Makerere University who have experienced intimate partner violence
(Makerere University, 2025)Background: Depression among university students is a growing public health concern, particularly in those who have experienced intimate partner violence (IPV). Understanding the prevalence and associated factors is crucial ... -
Career development for infection and immunity research in Uganda: a decade of experience from the Makerere University - Uganda Virus Research Institute research and training programme
(African Academy of Science, 2020)Background: The Makerere University/Uganda Virus Research Institute (UVRI) Centre of Excellence for Infection & Immunity Research and Training (MUII) is a collaborative programme supporting excellence in Infection and ... -
Intention to use immediate postpartum contraception and associated factors amongst mothers delivering from Kisenyi and Kawaala HC IVs
(Makerere University, 2025)Background:. The global prevalence of unintended pregnancies is about 41%, and 40% in low and middle-income countries. A study in Yumbe district indicated the prevalence of short birth intervals of 52.4%, from which 12% ... -
Frequency, course, outcomes and factors associated with delirium among adult patients admitted to Uganda Cancer Institute
(Makerere University, 2025)Background: Delirium is a neurocognitive disorder that commonly affects patients with cancer. Among patients with cancer admitted to oncology units, the prevalence varies from 18% to 33% and the incidence varies from 3.5% ... -
The Clinical Presentation and Factors Associatedwith Disease Severity of Rheumatoid Arthritis inUganda: A Cross-Sectional Study
(2022)Background Rheumatoid arthritis (RA) is a chronic, debilitating disease that leads to joint destruction and disability if left untreated. Few studies on RA have been conducted in Uganda, and there is limited information ... -
Prevalence of arps10, fd, pfmdr-2, pfcrt and pfkelch13 gene mutations in Plasmodium falciparum parasite population in Uganda
(PloS ONE, 2022)In Uganda, Artemether-Lumefantrine and Artesunate are recommended for uncomplicated and severe malaria respectively, but are currently threatened by parasite resistance. Genetic and epigenetic factors play a role in ... -
Identification of pathogen genomic differences that impact human immune response and disease during cryptococcus neoformans infection
(American Society for Microbiology, 2019)Patient outcomes during infection are due to a complex interplay between the quality of medical care, host immunity factors, and the infecting pathogen’s characteristics. To probe the influence of pathogen genotype on human ... -
Assessment of parasite clearance following treatment of severe malaria with intravenous artesunate in Ugandan children enrolled in a randomized controlled clinical trial
(BMC, 2018)Background Malaria control largely depends on availability of highly efficacious drugs, however, over the years, has been threatened by emergence of drug resistance. It is, therefore, important to monitor the impact of ... -
Contrasting impact of rural, versus urban, living on glucose metabolism and blood pressure in Uganda
(Wellcome Open research, 2020)Background: The burden of cardiometabolic diseases, including cardiovascular diseases and diabetes, is increasing in sub-Saharan Africa and this has been linked to urbanisation. Helminths, through their immunomodulatory ... -
Defining gaps in pre-exposure prophylaxis delivery for pregnant and post-partum women in high-burden settings using an implementation science framework
(Elsevier, 2020)Pregnancy is a high-risk period for HIV acquisition in African women, and pregnant women who become acutely infected with HIV account for up to a third of vertical HIV transmission cases in African settings. To protect ... -
Sustained positive impact on tuberculosis treatment outcomes of TB-HIV integrated care in Uganda
(The Union, 2019)OBJECTIVE: To examine tuberculosis (TB) treatment outcomes from a long-term TB-HIV (human immunodeficiency virus) integrated model of care at the Infectious Diseases Institute Clinic, Kampala, Uganda. METHODS: We included ... -
Performance of lipoarabinomannan assay using cerebrospinal fluid for the diagnosis of tuberculous meningitis among HIV patients
(Wellcome Open Research, 2019)Background: The diagnostic utility of the Mycobacteria tuberculosis lipoarabinomannan (TB-LAM) antigen lateral flow assay on cerebrospinal fluid (CSF) for the diagnosis of tuberculous meningitis (TBM) has not been extensively ... -
A public health approach to cervical cancer screening in Africa through community-based self-administered HPV testing and mobile treatment provision
(Wiley, 2020)The World Health Organization (WHO) refers to cervical cancer as a public health problem, and sub-Saharan Africa bears the world's highest incidence. In the realm of screening, simplified WHO recommendations for low-resource ...