Browsing College of Health Sciences (CHS) by Author "Nakanjako, Damalie"
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Acceptance of routine testing for HIV among adult patients at the medical emergency unit at a national referral hospital in Kampala, Uganda
Nakanjako, Damalie; Kamya, Moses; Kyabayinze, Daniel; Mayanja-Kizza, Harriet; Freers, Jurgen; Whalen, Christopher; Katabira, Elly (2006)HIV testing is an entry point to comprehensive HIV/AIDS prevention and care. In Uganda, Routine Testing and Counseling for HIV (RTC) is not widely offered as part of standard medical care in acute care settings. This study ... -
Access to HIV/AIDS care for mothers and children in sub-Saharan Africa: adherence to the postnatal PMTCT program
Nassali, Mercy; Nakanjako, Damalie; Kyabayinze, Daniel; Beyeza, Jolly; Okoth, Anthony; Mutyaba, Twaha (Taylor & Francis (Routledge), 2009-09)Despite scale up of perinatal prevention of mother-to-child transmission (PMTCT) of HIV interventions,postnatal continuity of comprehensive HIV/AIDS care, for both the mother and baby, remains a challenge in developing ... -
Baseline severe anaemia should not preclude use of zidovudine in antiretroviral-eligible patients in resource-limited settings
Kiragga, Agnes N; Castelnuovo, Barbara; Nakanjako, Damalie; Manabe, Yukari C (BioMed Central, 2010)Background: Stavudine is no longer recommended as part of first-line therapy for patients initiating antiretroviral therapy (ART) in Uganda. Most patients are currently initiated on zidovudine-containing regimens, which ... -
A century of health professions’ education, training, academic research and service at Makerere University, Kampala, Uganda
Nakanjako, Damalie; Omaswa, Francis (DOI, 2022)The Makerere University College of Health Sciences traces its history to 1924, when Makerere University Medical School was established as a medical training University unit in East and Central Africa; drawing trainees from ... -
Doctoral training in Uganda: evaluation of mentoring best practices at Makerere University College of Health Sciences
Nakanjako, Damalie; Katamba, Achilles; Kaye, Dan K.; Okello, Elialilia; Kamya, Moses R.; Sewankambo, Nelson; Mayanja-Kizza, Harriet (BMC Medical Education, 2014)Background: Good mentoring is a key variable for determining success in completing a doctoral program. We identified prevailing mentoring practices among doctoral students and their mentors, identified common challenges ... -
Effect of home based water chlorination and safe storage on diarrhea among persons with human immonodeficiency virus in Uganda.
Lule, John R.; Mermin, Jonathan; Ekwaru, John Paul; Malamba, Samuel; Downing, Robert; Ransom, Raymond; Nakanjako, Damalie; Wafula, Winnie; Hughes, Peter; Bunnell, Rebecca; Kaharuza, Frank; Coutinho, Alex; Kigozi, Aminah; Quick, Robert (American Society of Tropical Medicine and Hygiene, 2005)Diarrhea is frequent among persons infected with human immunodeficiency virus (HIV) but few interventions are available for people in Africa. We conducted a randomized controlled trial of a home-based, safe water intervention ... -
Eligibility for HIV/AIDS treatment among adults in a medical emergency setting at an urban hospital in Uganda
Nakanjako, Damalie; Kyabayinze, Daniel J.; Mayanja-Kizza, Harriet; Kamya, Moses R; Katabira, Elly (Makerere University Medical School, 2007)Background: Despite global effort to scale up access to antiretroviral therapy (ART), many people in need of HIV/AIDS care in Uganda have not been reached. HIV testing and ART are not widely offered as routine medical ... -
High CD56++CD16- natural killer (NK) cells among suboptimal immune responders after four years of suppressive antiretroviral therapy in an African adult HIV treatment cohort
Bayigga, Lois; Nabatanzi, Rose; Naluyima Sekiziyivu, Prossy; Mayanja-Kizza, Harriet; Kamya, Moses R.; Kambugu, Andrew; Olobo, Joseph; Kiragga, Agnes; Kirimunda, Sam; Joloba, Moses; Nakanjako, Damalie (BMC Immunology, 2014)Background: Up to 40% of HIV-infected individuals receiving Highly Active Antiretroviral Therapy (HAART) have poor CD4+ T-cell recovery. The role of natural killer (NK) cells in immune recovery during HAART is not well ... -
High prevalence of glaucoma among patients in an Onchocerciasis Endemic Area (Mahenge, Tanzania)
Otiti-Sengeri, Juliet; Omaido, Blair Andrew; Bhwana, Dan; Nakanjako, Damalie; Missiru, Malik; Muwonge, Musa; Amara, Luis-Jorge; Mmbando, Bruno P.; Colebunders, Robert (MDPI, 2022)Onchocerciasis is known to cause skin lesions and blindness, but there is also epidemiological evidence that onchocerciasis is associated with epilepsy, including nodding syndrome. We carried out ocular exams in persons ... -
Impaired T-cell proliferation among HAARTtreated adults with suboptimal CD4 recovery in an African cohort
Nakanjako, Damalie; Ssewanyana, Isaac; Nabatanzi, Rose; Kiragga, Agnes; Kamya, Moses R.; Cao, Huyen; Mayanja-Kizza, Harriet (BMC Immunology, 2013)Background: Most HIV-infected subjects exhibit a progressive rise in CD4 T-cell counts after initiation of highly active antiretroviral therapy (HAART). However, a subset of individuals exhibit very poor CD4 T-cell recovery ... -
Longitudinal patients’ cohorts for impactful research and HIV care at the Infectious Diseases Institute
Castelnuovo, Barbara; Kamya, Moses; Ratanshi, Rosalind Parkes; Kiragga, Agnes N.; Nakanjako, Damalie (2022)Introduction Observational studies provide important evidence supporting the feasibility and effectiveness of health interventions. The 20-year-old Infectious Diseases Institute (IDI) established to respond to infectious ... -
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
Nanyeenya, Nicholus; Kiwanuka, Noah; Nakanjako, Damalie; Nakigoz, Gertrude; Kibira, Simon P.S.; Nabadda, Susan; Kiyaga, Charles; Sewanyana, Isaac; Nasuuna, Esther; Makumbi, Fredrick (AOSIS, 2022)Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to achieve global Sustainable ... -
Makerere University-Uganda Heart Institute collaborative cardiovascular disease training and research since 1988
Okello, Emmy; Ssemogerere, Lameck; Ssinabulya, Isaac; Kayima, James; Nakanjako, Damalie; Sebatta, Elias; Lubega, Sulaiman; Oketcho, Michael; Mwambu, Tom; Lwabi, Peter; Mijumbi, Cephas; Omagino, John (2022)Background Makerere University College of Health Sciences has been collaborating with the Uganda Heart Institute to build capacity for research, training and clinical care in cardiovascular medicine for the last 34 years ... -
Microbial characteristics of dental caries in HIV positive individuals
Kalanzi, Dunstan; Mayanja-Kizza, Harriet; Nakanjako, Damalie; Semitala, Fred; Mboowa, Gerald; Mbabali, Muhammad; Kigozi, Edgar; Katabazi, Fred Ashaba; Sserwadda, Ivan; Kateete, David P.; Achan, Beatrice; Sewankambo, Nelson K.; Muwonge, Adrian (2022)Background: Dental caries is a multifactorial disease that affects many people. Even though microorganisms play a crucial role in causing dental caries, diagnosis is routinely macroscopic. In order to improve early detection ... -
Mobile Phone-based intervention to promote un-interrupted HIV treatment during the COVID-19 pandemic
Nakanjako, Damalie; Mayanja, Eisah Kakyama; Rwashana, Agnes Semwanga; Semitala, Fred; Katureebe, Cordelia; Ssali, Mina; Muddu, Martin; Ssinabulya, Isaac (2022)Introduction: Keeping HIV-infected adults away from the health care system during the COVID-19 travel restrictions, presents a challenge to HIV treatment adherence. Methods: This study focused on the initial two phases ... -
A need to accelerate health research productivity in an African University: the case of Makerere University College of Health Sciences.
Nakanjako, Damalie; Akena, Dickens; Kaye, Dan K.; Tumwine, James; Okello, Elialilia; Kamya, Moses R.; Nakimuli, Annettee; Kambugu, Andrew; McCullough, Hazel; Mayanja-Kizza, Harriet; Sewankambo, Nelson K. (Health Research Policy and Systems, 2017)Background: In the last decade, Makerere University College of Health Sciences (MakCHS) has taken strides in research and training to improve healthcare through collaborative training and research programs. However, ... -
Strategies to optimize HIV treatment outcomes in resource-limited settings
Nakanjako, Damalie; Colebunders, Robert; Coutinho, Alex G.; Kamya, Moses R. (Permanyer Publications, 2009)Although the availability of antiretroviral therapy has increased rapidly to reach over three million people in low- and middle-income countries, coverage remains low as only 31% of people in need were receiving antiretroviral ... -
Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on Antiretroviral Therapy (ART) in sub-Saharan Africa: Frequency and clinical significance
Nakanjako, Damalie; Kiragga, Agnes; Ibrahim, Fowzia; Castelnuovo, Barbara; Kamya, Moses R.; Easterbrook, Philippa J. (BioMed Central, 2008-10)Background: A proportion of individuals who start antiretroviral therapy (ART) fail to achieve adequate CD4 cell reconstitution despite sustained viral suppression. We determined the frequency and clinical significance of ... -
Sub-optimal vitamin B-12 levels among ART-Naïve HIV positive individuals in an urban cohort in Uganda
Semeere, Aggrey S.; Nakanjako, Damalie; Ddungu, Henry; Kambugu, Andrew; Manabe, Yukari C.; Colebunders, Robert (Public Library of Science, 2012-07-02)Malnutrition is common among HIV-infected individuals and is often accompanied by low serum levels of micronutrients. Vitamin B-12 deficiency has been associated with various factors including faster HIV disease progression ... -
Subclinical atherosclerosis among HIV-infected adults attending HIV/AIDS care at two large Ambulatory HIV clinics in Uganda
Ssinabulya, Isaac; Kayima, James; Longenecker, Chris; Mary Luwedde, Mary; Fred Semitala, Fred; Kambugu, Andrew; Ameda, Faith; Sam Bugeza, Sam; McComsey, Grace; Freers, Juergen; Nakanjako, Damalie (PLOS One, 2014)Background: The increased immune activation and inflammation of chronic HIV-infection and the characteristic dyslipidemias associated with HIV infection and antiretroviral therapy (ART) contribute to an increased risk of ...