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Assessment of availability of antimalarials and providers’ knowledge on malaria and antimalarials in private pharmaceutical outlets of Bushenyi District
(Makerere University, 2010-07)
Introduction: Malaria is the leading cause of morbidity and mortality and the cause of significant economic losses in Uganda and Bushenyi District. As a response to increasing levels of antimalarial resistance National ...
Genetic polymorphisms in plasmodium falciparum associated with resistance to artemisinin combination therapy: complexity of infection during short-term culture and characterization of in vitro sensitivity in Kampala Uganda
(Makerere University, 2010)
Background: Artemisinin-based combination therapy (ACT) is currently advocated in Africa as a means of improving treatment efficacy and slowing the development of drug resistance. However, the selection of resistant ...
Chlorproguanil-dapsone for treating uncomplicated malaria (Review)
(JohnWiley & Sons, 2010)
Background In Africa, malaria is often resistant to chloroquine and sulfadoxine-pyrimethamine. Chlorproguanil-dapsone is a potential alternative. Objectives To compare chlorproguanil-dapsone with other antimalarial drugs ...
Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort
(Elsevier, 2010-03-29)
Background: Co-trimoxazole prophylaxis can reduce mortality from untreated HIV infection in Africa; whether benefits occur alongside combination antiretroviral therapy (ART) is unclear. We estimated the effect of prophylaxis ...
Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria (Review)
(Cochrane Collaboration, 2010)
Background
Multiple-drug-resistant malaria is widespread, and in South-East Asia resistance is high against nearly all single therapy antimalarial drugs. Here, and in other areas with low malaria transmission, the combination ...
Genetic polymorphisms in plasmodium falciparum associated with resistance to artemisnin combination therapy: complexity of infection during short-term culture and characterization of in-vitro sensitivity in Kampala Uganda
(2010)
Background Artemisinin-based combination therapy (ACT) is currently advocated in Africa as a means of improving treatment efficacy and slowing the development of drug resistance. However, the selection of resistant parasites, ...
Plasma levels of DDT/DDE and liver function in malaria control personnel prior to DDT in-door residual spray in Northern Uganda, 2008
(African Journal of Animal and Biomedical Sciences, 2010)
Where 20 million Ugandans are debilitated by malaria in a year, there is continued need of
dichlorodiphenyltrichloroethane (DDT) for vector control while further research is implemented to clarify the
health impact of ...
Plasma levels of DDE/DDT and liver function in malaria control personnel 6 months after indoor residual spraying with DDT in Northern Uganda, 2008
(The South African Medical Journal, 2010-02)
Objective. We investigated the relationship between plasma levels of dichlorodiphenyltrichloroethane (DDT) and liver function in malaria control personnel 6 months after one round of DDT indoor residual spraying (IRS).
Method. ...