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Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults
(BioMed Central, 2012-04-27)
Background: Severe malaria is a medical emergency with high mortality. Prompt achievement of therapeutic concentrations of highly effective anti-malarial drugs reduces the risk of death. The aim of this study was to assess ...
Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults
(Oxford University Press, 2012)
Objectives: Co-administration of artemether/lumefantrine with antiretroviral therapy has potential for pharmacokinetic drug interactions. We investigated drug–drug interactions between artemether/lumefantrine and efavirenz ...
Hemoglobin status and its association with age in children under five years in the Central Region of Uganda.
(Makerere University, 2012-04)
Background: The hemoglobin concentration is widely used as an aid in assessment of state of health. A sound factual basis is therefore necessary for establishing the trend of hemoglobin values its relation to age. WHO ...
Parasite-based diagnosis for malaria in Uganda: feasibility and cost-effectiveness
(Makerere University, 2012)
From 2006 the first-line treatment for uncomplicated malaria in Uganda was with
artemisinin-based combination therapy (ACT). In 2010, Uganda adopted the universal
parasite-based diagnosis for malaria before treatment ...