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Assessment of availability of antimalarials and providers’ knowledge on malaria and antimalarials in private pharmaceutical outlets of Bushenyi District
(Makerere University, 2010-07)
Introduction: Malaria is the leading cause of morbidity and mortality and the cause of significant economic losses in Uganda and Bushenyi District. As a response to increasing levels of antimalarial resistance National ...
Genetic polymorphisms in plasmodium falciparum associated with resistance to artemisinin combination therapy: complexity of infection during short-term culture and characterization of in vitro sensitivity in Kampala Uganda
(Makerere University, 2010)
Background: Artemisinin-based combination therapy (ACT) is currently advocated in Africa as a means of improving treatment efficacy and slowing the development of drug resistance. However, the selection of resistant ...
Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults
(Oxford University Press, 2012)
Objectives: Co-administration of artemether/lumefantrine with antiretroviral therapy has potential for pharmacokinetic drug interactions. We investigated drug–drug interactions between artemether/lumefantrine and efavirenz ...