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Uptake and challenges in implementation of early infant diagnosis of HIV in Arua District, Northwest Uganda
(Makerere university, 2022-04-11)
Background: Human Immunodeficiency Virus (HIV) infected infants have a 35–40% risk of death in the first year of life from HIV related morbidity, if not started on lifelong antiretroviral therapy (ART). The integration of ...
Comparison of semi-parametric and parametric survival analysis models for identifying predictors of virological suppression among HIV-infected adults on ART at the Joint Clinical Research Centre, Uganda
(Makerere University, 2022-04-29)
Background: Semi-parametric and parametric survival analysis models have been widely used to analyze the effects of covariates on survival time. The Cox proportional hazards (PH) model in particular remains the most popular ...
Simulation of clonal expansion and latent HIV reservoir size prediction using machine learning in virally suppressed individuals in Uganda
(Makerere University, 2022-07)
Background: HIV can survive as pro-viruses that do not undergo transcription mostly within resting memory CD4+ T cells despite prolonged antiretroviral therapy (ART). This Latent Viral Reservoir (LVR) has an extremely long ...
HIV risk and factors associated with use of novel prevention interventions among female students at Makerere University
(Makerere University, 2022)
Introduction: Adolescent girls and young women (AGYW), aged 15-24 years, account for 1 in 4 new HIV infections in sub-Saharan Africa. Female university students are members of this key population. Female university students ...
Assessment of microbiological quality of herbal preparations used in the treatment of malaria, cough and HIV in Kampala district
(Makerere University, 2022-02)
In Uganda, herbal medicine is widely used in the treatment and prevention of various conditions including cough, malaria and HIV opportunistic infections. The demand for herbal products has increased among many consumers ...
Prevalence and factors associated with selected non-Communicable diseases among HIV patients at Kalisizo Hospital in Kyotera District-Uganda
(Makerere university, 2022-07-01)
Background: Successful rollout of highly active antiretroviral therapy has improved survival and ageing among persons living with HIV. Opportunistic infections are declining as the leading cause of morbidity and mortality ...
Retention in HIV care among adolescents living with HIV at Naguru Hospital: Effect of COVID-19 restrictive measures and other associated factors
(Makerere University, 2022-12)
Introduction; In 2020, there were about 1.75 million adolescents living with HIV (ALWHIV) around the world. Approximately 1.5 million HIV-infected adolescents were from Sub-Saharan Africa, and by the end of 2019, about 7% ...
Low-abundance drug resistant variant patterns among HIV-1 patients with virological failure in Uganda
(Makerere University, 2022-03)
Background: The emergence and spread of antiretroviral drug resistant HIV-1 variants is one
of the major factors responsible for therapeutic failure in persons living with HIV (PLWH) as
it jeopardizes the efforts to ...
Using Intervention Mapping methodology to design an HIV linkage intervention in a refugee settlement in rural Uganda.
(AIDS Care, 2022)
Nearly 80 million people have been forcibly displaced by persecution, violence, and disaster. Displaced populations, including refugees, face health challenges such as resource shortages, food and housing insecurity, ...
Prevalence and factors associated with hypertension among adults on dolutegravir based antiretroviral therapy in Mengo Hospital
(Makerere University, 2022-03-30)
Introduction
Dolutegravir (DTG) based anti-retroviral therapy (ART) regimens have been rolled out in Uganda due to their effectiveness in the management of Human immunodeficiency virus
(HIV). However, reports from developed ...