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Role of Killer-cell Immunoglobulin-like Receptors and Human Leukocyte Antigens in Transmission and Severity of Malaria in Uganda
(Makerere University, 2021-04-08)
Background
Malaria is a life-threatening disease caused by Plasmodium falciparum. In 2018, there were an estimated 228 million cases of malaria worldwide and 405,000 malaria deaths. Malaria burden is greatly affected by ...
The impact of maternal soluble human leukocyte Antigen-G levels on risk to malaria in infants at Masafu, Busia, Uganda
(Makerere University, 2021-04-29)
Background: HLA-G is known to play a vital role in protection of the fetus in utero against maternal natural killer cells, but it is associated with progression of both viral and parasitic infection such as Plasmodium ...
Integration of DHIS2 and Climatic data for disease prediction: A case of malaria occurrence in Gulu District, Uganda
(Makerere University, 2021-01)
Background and Purpose: Prediction models are important tools that can assist public health in evidence based decision making. Since 1950, Uganda has had several prevention and control interventions but malaria is still ...
Host genetic variations and their association with malaria among Ugandan children
(Makerere University, 2021-04)
This thesis comprises studies of the relationship between host genetic factors and incidence of uncomplicated malaria in a vaccine trial site in Iganga district. The studies focused on selected host gene markers that are ...
Malaria case management and associated factors for children under-five years at Abim and Kaabong General Hospitals in Karamoja Sub-Region, Uganda
(Makerere university, 2021-03)
Introduction: Malaria still remains a global health concern, despite the availability of effective prevention and treatment measures. Inappropriate case management is one of the known risk factors for disease progression ...