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Simulation of clonal expansion and latent HIV reservoir size prediction using machine learning in virally suppressed individuals in Uganda
(Makerere University, 2022-07)
Background: HIV can survive as pro-viruses that do not undergo transcription mostly within resting memory CD4+ T cells despite prolonged antiretroviral therapy (ART). This Latent Viral Reservoir (LVR) has an extremely long ...
Low-abundance drug resistant variant patterns among HIV-1 patients with virological failure in Uganda
(Makerere University, 2022-03)
Background: The emergence and spread of antiretroviral drug resistant HIV-1 variants is one
of the major factors responsible for therapeutic failure in persons living with HIV (PLWH) as
it jeopardizes the efforts to ...
Retention in HIV care and associated factors among young breastfeeding mothers on lifelong antiretroviral therapy in selected sites in Soroti district
(Makerere University, 2022-12-05)
Introduction: Pregnant and postpartum adolescents aged 15-19 years and young women aged 20-24 years living with HIV are at a higher risk of being lost from antenatal care and ART services. They are also less likely to ...
Correlation of plasma HIV-1 p24 antigen levels with viral load in samples of HIV positive patients on ART in Uganda
(Makerere University, 2022-12)
Globally, a total of 38.0 million people living with HIV, of which 1.7 million people became newly infected with HIV in 2019. Additionally, an average of 690,000 people died from AIDS-related illnesses in 2019, and 26 ...