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Practices of diagnosis and treatment of pulmonary tuberculosis, associated factors, barriers and facilitators among private practitioners in Kampala, Uganda
(Makerere University, 2020-11)
Introduction: Globally, tuberculosis (TB) is a leading cause of morbidity and mortality accounting for an estimated 10.0 million new cases and 1.451million deaths in 2018. Uganda is one of the world’s high TB burden countries ...
Effect of vitamin d binding protein gene polymorphisms and vitamin d bioavailability on cathelicidin expression in tuberculosis infection and disease
(Makerere University, 2023-01)
Background: The human antimicrobial peptide cathelicidin (LL-37) is involved in host innate immunity by the after activation of Toll-like receptors (TLRs), resulting in direct killing of Mycobacterium tuberculosis (MTB). ...
Patient single nucleotide polymorphisms assiocated with Mycobacterium tuberculosis genotypes in Ugandan population
(Makerere University, 2022-12)
Uganda is one of the 30 World Health Organization-designated countries with a high burden of TB/HIV, with three main dominant genotypes that cause tuberculosis. Recent studies have shown that the M. tuberculosis Uganda ...
Performance evaluation of the Uganda National Algorithm for Diagnosis of tuberculosis in children at Mulago National Referral Hospital-Kampala, Uganda
(Makerere University, 2023)
Background
Diagnosing childhood tuberculosis (TB) is a challenge, this led the Uganda national tuberculosis control program (NTLP) to develop a clinical treatment decision algorithm for children. However, there is limited ...