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Steady state bioequivalence of generic and innovator formulations of stavudine, lamivudine, and nevirapine in HIV-infected Ugandan adults
(Public Library of Science, 2008-12-19)
Background: Generic antiretroviral therapy is the mainstay of HIV treatment in resource-limited settings, yet there is little evidence confirming the bioequivalence of generic and brand name formulations. We compared the ...
Voices on adherence to ART in Ethiopia and Uganda: a matter of choice or simply not an option
(Routledge - Taylor & Francis, 2009)
This paper explores HIV patients’ adherence to antiretroviral treatment (ART) in resource-limited contexts in Uganda and Ethiopia, where ART is provided free of charge. Qualitative semi-structured interviews were conducted ...
Potential impact of task-shifting on costs of antiretroviral therapy and physician supply in Uganda
(BMC Health Services Research, 2009-01-09)
Background Lower-income countries face severe health worker shortages. Recent evidence suggests that this problem can be mitigated by task-shifting—delegation of aspects of health care to less specialized health workers. ...
The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala, Uganda
(Makerere University Medical School, 2008-03)
Background: Liver diseases are common in patients with HIV due to viral hepatitis B and C co-infections, opportunistic infections or malignancies, antiretroviral drugs and drugs for opportunistic infections. Objective: To ...
Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy
(CID, 2008)
Background. Cryptococcal meningitis (CM) is the proximate cause of death in 20%–30% of persons with acquired immunodeficiency syndrome in Africa. Methods. Two prospective, observational cohorts enrolled human immunodeficiency ...
Symptomatic hyperlactatemia associated with nucleoside analogue reverse-transcriptase inhibitor use in HIV-infected patients: a report of 24 cases in a Resource-Limited Setting (Uganda).
(University of Chicago Press, 2007)
We describe 24 Ugandan patients with human immunodeficiency virus infection who developed symptomatic hyperlactatemia associated with the use of nucleoside analogues. All patients were receiving combination therapy that ...
Longitudinal antiretroviral adherence in HIV+ Ugandan parents and their children initiating HAART in the MTCT-plus family treatment model: role of depression in declining adherence over time.
(Springer, 2009-03-20)
We conducted a study to assess the effect of family-based treatment on adherence amongst HIV-infected parents and their HIV-infected children attending the Mother-To-Child-Transmission Plus program in Kampala, Uganda. ...
Total lymphocyte count of 1200 is not a sensitive predictor of CD4 lymphocyte count among patients with HIV disease in Kampala, Uganda
(Makerere University Medical School, 2004-08)
Introduction: Total Lymphocyte Count (TLC) has been found to be an inexpensive and useful marker for staging disease, predicting progression to AIDS and death and monitoring response to ART. However, the correlation between ...
Relationship between plasma levels of stavudine and self reported adherence rates to triomune in HIV/AIDS patients at the Joint Clinical Research Centre, Mengo Uganda.
(2009)
INTRODUCTION:
Adherence to antiretroviral therapy is mainly assessed by patient self reporting method in Uganda. The relationship between self reported adherence rates and plasma drug levels is not known. This study sought ...
Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?
(Open Learning on Enteric Pathogens, 2009-03)
A large number of patients are switched to second-line antiretroviral therapy, especially in resource limited settings. Lopinavir/Ritonavir is the main drug used in second-line treatment regimens. We describe a patient ...