Browsing School of Health Sciences (Health-Sciences) by Subject "Africa"

Now showing items 1-20 of 23

    • Caregivers' experience with major depression concealed by physical illness in patients recruited from Central Ugandan Primary Health Care centers 

      Muhwezi, Wilson Winstons; Okello, Elialilia Sarikiaeli; Neema, Stella; Musisi, Seggane (Sage Publications, 2008)
      In this article, we present caregivers’ grapples with major depression seen among their physically ill patients. A thematic analysis of 29 in-depth caregiver interviews identified four themes: (a) caregivers’ perceptions ...

    • The challenge to restoring basic health care in Uganda 

      Okello, D.O; Lubanga, R.; Guwatudde, D.; Sebina-Zziwa, A. (Elsevier Science, 1998)
      This paper presents the results of a health facility survey conducted in Uganda between June 1992 and December 1993. The survey covered both government and non-government organization (NGO) facilities from 10 districts in ...

    • Chlorproguanil-dapsone for treating uncomplicated malaria (Review) 

      Bukirwa, H.; Critchley, J.A; Garner, P. (JohnWiley & Sons, 2010)
      Background In Africa, malaria is often resistant to chloroquine and sulfadoxine-pyrimethamine. Chlorproguanil-dapsone is a potential alternative. Objectives To compare chlorproguanil-dapsone with other antimalarial drugs ...

    • Citywide trauma experience in Kampala, Uganda: a call for intervention 

      Kobusingye, O.C; Guwatudde, D.; Owor, G; Lett, R.R (BMJ Publishing Group, 2002)
      Objectives: To describe injuries and their emergency care at five city hospitals. Setting: Data were collected between January and December 1998 from casualty departments of the five largest hospitals of Kampala city, ...

    • Community effectiveness of malaria treatment in Uganda: a long way to Abuja targets 

      Nsungwa-Sabiiti, Jesca; Tomson, Goran; Pariyo, George; Ogwal-Okeng, Jasper; Peterson, Stefan (Taylor & Francis, 2005)
      Introduction: At the Roll Back Malaria summit for African countries in Abuja, the heads of state committed to ensure that by the year 2005 at least 60% of those suffering from malaria would have access to effective treatment ...

    • Complexity of plasmodium falciparum infections and antimalarial drug efficacy at 7 sites in Uganda. 

      Sulggi, Less A.; Nsobya, Samuel L.; Yeka, Adoke; Dokomajilar, Christian; Rosenthal, Philip J.; Talisuna, Ambrose; Dorsey, Grant (University of Chicago Press, 2006-03-13)
      Malaria infections in Africa frequently include multiple parasite strains.We examined the relationship between the number of infecting Plasmodium falciparum strains and the responses to 3 different combination therapies ...

    • The costs and effectiveness of four HIV counseling and testing strategies in Uganda 

      Menzies, Nick; Abang, Betty; Wanyenze, Rhoda; Nuwaha, Fred; Mugisha, Balaam; Coutinho, Alex; Bunnell, Rebecca; Mermin, Jonathan; Blandford, John M. (Lippincott, Williams & Wilkins, 2009)
      Objective: HIV counseling and testing (HCT) is a key intervention for HIV/AIDS control, and new strategies have been developed for expanding coverage in developing countries. We compared costs and outcomes of four HCT ...

    • Digital clubbing in tuberculosis – relationship to HIV infection, extent of disease and hypoalbuminemia 

      Ddungu, Henry; Johnson, John L; Smieja, Marek; Mayanja-Kizza, Harriet (BioMed Central, 2006-03-10)
      Background: Digital clubbing is a sign of chest disease known since the time of Hippocrates. Its association with tuberculosis (TB) has not been well studied, particularly in Africa where TB is common. The prevalence of ...

    • Effect of home based water chlorination and safe storage on diarrhea among persons with human immonodeficiency virus in Uganda. 

      Lule, John R.; Mermin, Jonathan; Ekwaru, John Paul; Malamba, Samuel; Downing, Robert; Ransom, Raymond; Nakanjako, Damalie; Wafula, Winnie; Hughes, Peter; Bunnell, Rebecca; Kaharuza, Frank; Coutinho, Alex; Kigozi, Aminah; Quick, Robert (American Society of Tropical Medicine and Hygiene, 2005)
      Diarrhea is frequent among persons infected with human immunodeficiency virus (HIV) but few interventions are available for people in Africa. We conducted a randomized controlled trial of a home-based, safe water intervention ...

    • Estimating the healthcare burden of osteomyelitis in Uganda 

      Beyeza, Titus; Stanley, Christine M.; Rutherford, George W.; Morshed, Saam; Coughlin, Richard R. (Elsevier, 2009-08-25)
      Chronic osteomyelitis is a considerable healthcare burden in many developing countries, but this burden is poorly quantified. To estimate the clinical burden of osteomyelitis we systematically sampled the medical records ...

    • Ethical oversight of multinational collaborative research: lessons from Africa for building capacity and for policy 

      Sugarman, Jeremy; Ocama, Ponsiano (The Association of Research Ethics Committees, 2007)
      Researchers and others involved in the research enterprise from 12 African countries met with those working in ethics and oversight in the United States as part of an effort to develop research ethics capacity. Drawing on ...

    • Injury patterns in rural and urban Uganda 

      Kobusingye, O.; Guwatudde, D; Lett, R (BMJ Publishing Group, 2001)
      Objectives—To describe and contrast injury patterns in rural and urban Uganda. Settings—One rural and one urban community in Uganda. Methods—Community health workers interviewed adult respondents in households selected by ...

    • Linkage to HIV care and survival following inpatient HIV counseling and testing 

      Wanyenze, Rhoda K (Springer, 2010)
      Linkage to HIV care and survival in sub-Saharan Africa is not well documented. In 2004 we conducted a randomized trial among medical inpatients in Mulago Hospital to assess the impact of HIV counseling and testing (HCT) ...

    • The liver in HIV in Africa 

      Ocama, Ponsiano; Feld, Jordan J; Ronald, Allan (International Medical Press, 2005)
      As access to antiretroviral therapy improves across the African continent, liver disease is emerging as an important cause of morbidity and mortality among HIV-infected individuals. Although coinfection with hepatitis B ...

    • Nutritional status and its determinants in children under five years of age in Rweibaare Parish, Bushenyi District. 

      Damulira, Adam (2005)
      Under-nutrition and infection are the major causes of morbidity and mortality in the developing world. These two problems are interrelated. Under-nutrition compromises barrier function, allowing easier access by pathogens, ...

    • Spatial phylodynamics of HIV-1 epidemic emergence in East Africa. 

      Serwadda, David; Gray, Rebecca R.; Tatem, Andrew J.; Lamers, Susanna; Hou, Wei; Laeyendecker, Oliver; Sewankambo, Nelson; Gray, Ronald H.; Wawer, Maria J.; Quinn, Thomas C.; Goodenow, Maureen M.; Salemi, Marco (2009-09-11)
      Design—We sought to investigate the evolutionary and historical reasons for the different epidemiological patterns of HIV-1 in the early epidemic. In order to characterize the demographic history of HIV-1 subtypes A and D ...

    • Suicide in urban Kampala, Uganda: a preliminary exploration 

      Kinyanda, E.; Wamala, D.; Musisi, S.; Hjelmeland, H (Makerere University Medical School, 2011-06)
      Background: Suicide was investigated in the urban setting of Kampala, Uganda. Objectives: Firstly, to explore the use of two research methodologies, a retrospective review of patient records and the psychological autopsy ...

    • Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multisite trial to guide national policy in Uganda 

      Bakyaita, Nathan; Dorsey, Grant; Adoke, Yeka; Banek, Kristin; Staedke, Sarah G.; Kamya, Moses R.; Talisuna, Ambrose; Kironde, Fred; Nsobya, Sam; Kilian, Albert; Reingold, Arthur; Rosenthal, Philip J.; Wabwire-Mangen, Fred (2005)
      The use of combinations of inexpensive drugs for the treatment of malaria in Africa has been proposed as an interim policy while awaiting the widespread availability of more effective regimens. We compared sulfadoxinepyrimethamine ...

    • Total lymphocyte count: not a surrogate marker for risk of death in HIV infected Ugandan children 

      Musoke, Philippa M.; Owor, Maxensia; Young, Alicia M.; Lubega, Irene R.; Brown, Elizabeth R.; Mmiro, Francis A.; Mofenson, Lynne M.; Jackson, J. Brooks; Fowler, Mary Glenn; Guay, Laura A. (Lippincott, Williams & Wilkins, 2008-10-01)
      Objectives—To determine the utility of Total Lymphocyte Count (TLC) in predicting the 12 month mortality in HIV infected Ugandan children; to correlate TLC and CD4 cell %. Design—This is a retrospective data analysis of ...

    • Treatment interruptions predict resistance in HIV-positive individuals purchasing fixed-dose combination antiretroviral therapy in Kampala, Uganda 

      Oyugi, Jessica H.; Byakika-Tusiime, Jayne; Ragland, Kathleen; Laeyendecker, Oliver; Mugerwa, Roy; Kityo, Cissy; Mugyenyi, Peter; Quinn, Thomas C.; Bangsberg, David R. (Lippincott, Williams & Wilkins, 2007)
      Objective: To evaluate adherence, treatment interruptions, and outcomes in patients purchasing antiretroviral fixed-dose combination (FDC) therapy. Design: Ninety-seven participants were recruited into a prospective 24-week ...