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Now showing items 41-50 of 88
Attitudes and perceptions about the Research and Ethics Committee in Kampala, Uganda
(Renaissance Medical Publishing, 2010)
Background: The Makerere University Faculty of Medicine Research and Ethics Committee reviews and approves more than 100 new research protocols a year, yet its activities had never been evaluated as far as the researchers ...
War related sexual violence and it’s medical and psychological consequences as seen in Kitgum, Northern Uganda: A cross-sectional study
(2010)
Background: Despite the recent adoption of the UN resolution 1820 (2008) which calls for the cessation of war related sexual violence against civilians in conflict zones, Africa continues to see some of the worst cases of ...
Treatment of chronic hepatitis B virus infection in resource-constrained settings: expert panel consensus
(John Wiley & Sons, 2010)
Most of the estimated 350 million people with chronic hepatitis B virus (HBV) infection live in resource-constrained settings. Up to 25% of those persons will die prematurely of hepatocellular carcinoma (HCC) or cirrhosis. ...
Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: A prospective cohort study
(PLoS Medicine, 2010)
Background: Although antiretroviral therapy (ART) improves survival in persons with cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution inflammatory syndrome (IRIS), an exaggerated and ...
Infection of multiple strains of micobacterium tuberculosis using MIRU-VNTR in patients with pulmonary tuberculosis in Kampala, Uganmda
(BioMed Central, 2010)
Background: Many studies using DNA fingerprinting to differentiate Mycobacterium tuberculosis (MTB) strains reveal single strains in cultures, suggesting that most disease is caused by infection with a single strain. ...
Comparison of methods in the recovery of nucleic acids from archival formalin-fixed paraffin-embedded autopsy tissues
(Elsevier, 2010-05)
Archival formalin-fixed paraffin-embedded (FFPE) human tissue collections are typically in poor states of storage across the developing world. With advances in biomolecular techniques, these extraordinary and virtually ...
Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans
(Lippincott Wilkins & Williams, 2010)
Abstract: Quinine is one of the most effective antimalarial drugs, although its clinical use is limited as a result of its narrow safety margin. Quinine is a substrate of the polymorphic p-glycoprotein and CYP3A4/3A5. This ...
Evaluation of the efficiency of patient flow at three HIV Clinics in Uganda
(Mary Ann Liebert, 2010)
With dramatic increases in antiretroviral therapy (ART) provision, many clinics in sub-Saharan Africa are congested, but little attention has focused on the efficiency of clinics. Between April and June 2008, we conducted ...
Linkage to HIV care and survival following inpatient HIV counseling and testing
(Springer, 2010)
Linkage to HIV care and survival in sub-Saharan Africa is not well documented. In 2004 we conducted a randomized trial among medical inpatients in Mulago Hospital to assess the impact of HIV counseling and testing (HCT) ...