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Now showing items 41-48 of 48
Update on the efficacy, effectiveness and safety of artemether–lumefantrine combination therapy for treatment of uncomplicated malaria
(Dove Medical Press, 2009)
Artemether–lumefantrine is one of the artemisisnin-based combination therapies recommended for treatment of uncomplicated falciparum malaria. The drug combination is highly efficacious against sensitive and multidrug ...
Treatment of severe sepsis with Artemether-Lumefantrine Is associated with decreased mortality in Ugandan patients without malaria
(American Society of Tropical Medicine and Hygiene, 2009)
We enrolled 382 patients at two hospitals in Uganda in a prospective observational study of severe sepsis. Because artemisinins improve survival in murine sepsis models, we performed a post hoc analysis of the association ...
Determination of Lamivudine, Zidovudine, and Nevirapine in capillary blood sampled on filter paper by LC
(Oxford University Press, 2009-11)
A bioanalytical method for determination of lamivudine (3TC), zidovudine (AZT), and nevirapine (NVP) in 100 μL capillary blood applied onto sampling paper has been developed and validated. The antiretroviral drugs (ARV) ...
Developing standard methods to monitor adherence to antiretroviral medicines and treatment defaulting in resource-poor settings
(2009)
Adherence to antiretrovirals is critical for longterm effective therapy with first-line medicines.This important study describes how groups from the International Network for the Rational Use of Drugs in East Africa developed ...
Characteristics of HIV-1 discordant couples enrolled in a trial of HSV-2 suppression to reduce HIV-1 transmission: the partners study.
(Public Library of Science, 2009-04-30)
Background: The Partners HSV-2/HIV-1 Transmission Study (Partners Study) is a phase III, placebo-controlled trial of daily acyclovir for genital herpes (HSV-2) suppression among HIV-1/HSV-2 co-infected persons to reduce ...
Trends in the incidence of primary liver cancer in Central Uganda, 1960-1980 and 1991-2005
(Nature Publishing Group, 2009)
Primary liver cancer (PLC) incidence trends from Africa are unknown. Using Kampala Cancer Registry data from 1960 to 1980 and 1991 to 2005, we identified 771 PLCs. Although rates were stable among men, PLC incidence among ...
The prevalence and factors associated with adrenal insufficiency among patients with sputum smear positive pulmonary tuberculosis admitted to Mulago Hospital.
(2009-09)
BACKGROUND:
Tuberculosis (TB) is still one of the common infections which cause adrenal insufficiency in the developing countries. That is why we set out to determine the prevalence and factors associated with adrenal ...
Prevalence, socio-demographic factors and antimicrobial susceptibility of neisseria gonorrhoea among men presenting with urethral discharge at Mulago and Murchison-bay Hospitals.
(2009)
INTRODUCTION:
Neisseria gonorrhoea remains a major sexually transmitted infection that is believed to be associated with increased risk of HIV transmission. It has shown an ever evolving pattern of increasing resistance ...