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Prevalence and factors associated with delayed ART initiation among HIV positive patients referred to Mulago ISS clinic in the test and treat era.
(Makerere University, 2021-12)
Background: In 2015, the World Health Organization (WHO) recommended the test and treat strategy due to evidence that early antiretroviral therapy (ART) prevented the pathophysiological progression of HIV to AIDS, reduced ...
Characteristics, survival and prognostic factors of adult patients with acute leukemia at the Uganda Cancer Institute
(Makerere University, 2021-12)
Background: Acute leukemias are rapidly progressive hematological malignancies associated with substantial morbidity and mortality, particularly in the adult population. In the past few decades, there is an increasing ...
Microbiological agents and their antimicrobial sensitivity patterns among patients with chronic osteomyelitis attending Mulago national referral and comprehensive rehabilitation services in Uganda hospitals
(Makerere University, 2021-11-02)
Introduction: Chronic osteomyelitis remains a big problem in low resource settings. Surgery, with antimicrobial treatment guided by culture and sensitivity are the treatments of choice. Poor choice of antibiotics could ...
Assessment of oral health status and associated factors among children with sickle cell disease at Mulago National Referral Hospital, Kampala.
(Makerere University, 2021-04-12)
Introduction
Sickle cell disease (SCD) is an inherited blood disorder, a lifelong condition that is commonly found in regions where malaria is endemic. SCD affects all tissues and organs of the body causing severe systemic ...
Willingness to donate samples for biobank research: factors associated, attitudes and perceptions of patients in Kiruddu General Hospital.
(Makerere University, 2021-03-31)
Background: There is a high unmet demand for human biospecimens in Africa for research. In response to this need, a biobank was established in Uganda with support from the human heredity and health in Africa (H3Africa) to ...
Evaluation of hepatitis b surface antigen (hbsag) as a surrogate marker for hepatitis b viral load estimation.
(Makerere University, 2021-04-28)
Background: A Hepatitis B Virus (HBV) viral load measurement is recommended for
diagnosis and monitoring of patients on treatment for Chronic Hepatitis B (CHB). However,
these diagnostic techniques are molecular-based ...
Evaluation of stool with sputum DNA on FTA card, microscope slide and TB-Lamp for Mycobacterium Tuberculosis detection using Xpert MTB/Rif (Xpert) as Gold standard among Pulmonary Tuberculosis patients
(Makerere University, 2021-04-19)
The Xpert MTB/RIF (Xpert) and TB-Lamp assay technology allows rapid and sensitive diagnosis of pulmonary tuberculosis (PTB) from sputum specimens. The conventional plastic sputum containers allow transportation of sputum ...
The impact of maternal soluble human leukocyte Antigen-G levels on risk to malaria in infants at Masafu, Busia, Uganda
(Makerere University, 2021-04-29)
Background: HLA-G is known to play a vital role in protection of the fetus in utero against maternal natural killer cells, but it is associated with progression of both viral and parasitic infection such as Plasmodium ...
Stakeholders perceptions and experiences regarding research at Makerere University College of Health Sciences
(Makerere University, 2021-02-17)
The study purposed to explore the perceptions and experiences of key research stakeholders at Makerere College of Health Sciences (MaKCHS) and affiliate research institutions. Several research studies conducted at the ...
M. Tuberculosis 85b messenger ribonucleic acid as a biomarker for treatment response among multidrug resistant tuberculosis patients attending Mulago hospital, Uganda
(Makerere University, 2021-04-28)
Background: The occurrence of multidrug resistance (MDR) is one of the major bottlenecks to TB elimination. This is worsened by the lack of reliable point of care (POC) tests for monitoring MDR TB patients with viable M. ...