Search

Now showing items 1-4 of 4

Differential prevalence of transporter polymorphisms in symptomatic and asymptomatic Falciparum Malaria Infections in Uganda

Tukwasibwe, Stephen; Mugenyi, Levi; Mbogo, George W.; Nankoberanyi, Sheila; Maiteki-Sebuguzi, Catherine; Joloba, Moses L.; Nsobya, Samuel L.; Staedke, Sarah G.; Rosenthal, Philip J. (Journal of Infectious Diseases, 2014)

We explored associations between Plasmodium falciparum drug resistance–mediating polymorphisms and clinical presentations in parasitemic children enrolled in a cross-sectional survey in Tororo, Uganda, using a retrospective ...

A metabolic biosignature of early response to anti-tuberculosis treatment

Mahapatra, Sebabrata; Hess, Ann M.; Johnson, John L.; Eisenach, Kathleen D.; DeGroote, Mary A.; Gitta, Phineas; Joloba, Moses L.; Kaplan, Gilla; Walz, Gerhard; Boom, W. Henry; Belisle, John T. (BMC Infectious Diseases, 2014)

Background: The successful treatment of tuberculosis (TB) requires long-term multidrug chemotherapy. Clinical trials to evaluate new drugs and regimens for TB treatment are protracted due to the slow clearance of Mycobacterium ...

Evaluation of capilia TB assay for rapid identification of mycobacterium tuberculosis complex in BACTEC MGIT 960 and BACTEC 9120 blood cultures

Muchwa, Christopher; Akol, Joseph; Etwom, Alfred; Morgan, Karen; Orikiriza, Patrick; Mumbowa, Francis; Odong, Paul R.; Kateete, David P; Eisenach, Kathleen D.; Joloba, Moses L. (BioMed Central, 2012)

Background: Capilia TB is a simple immunochromatographic assay based on the detection of MPB64 antigen specifically secreted by the Mycobacterium tuberculosis complex (MTC). Capilia TB was evaluated for rapid identification ...

Activation of the gab Operon in an RpoS-Dependent Manner by Mutations That Truncate the Inner Core of Lipopolysaccharide in Escherichia coli

Joloba, Moses L.; Clemmer, Katy M.; Sledjeski, Darren D.; Rather, Philip N. (American Society for Microbiology, 2004-12)

The gab operon (gabDTPC) in Escherichia coli functions in the conversion of -aminobutyrate to succinate. One component of gab operon regulation involves the RpoS sigma factor, which mediates activation at high cell density. ...