School of Bio-Medical Sciences (Bio-Medical): Recent submissions
Now showing items 181-200 of 418
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Healthcare workers’ experiences and processes undertaken in decision making for life-sustaining treatment in the intensive care units of Mulago National Referral, and Nakasero Hospitals
(Makerere University, 2022-04-28)Introduction: This study explored the experiences and processes undertaken by healthcare providers with regards to decision making for administering Life-Sustaining Treatment (LST) in Uganda. The specific objectives were: ... -
Attitudes and practices of herbalists towards the informed consent process
(Makerere University, 2022)Introduction: Informed Consent (IC) is a major cornerstone in medical ethics that is expected to be implemented universally in healthcare. The growing use of herbal medicines in developing countries has aroused concerns, ... -
Knowledge, attitudes and practice of ethics among plant agricultural researchers at the National Agricultural Research Laboratories, Kawanda-Uganda
(Makerere University, 2022-04-25)Background: Plant agricultural research plays an important role and contributes significantly to human health and livelihood. With the current advancements in technology, this research is not exempt from ethical issues and ... -
Internship Situation Analysis Survey Report
(College of Health Sciences, Makerere University, 2022-05)Internship is a mandatory pre-registration training required for licensure of doctors in Uganda. During the internship, medical workers acquire practical skills, attitudes and knowledge critical for them to work without ... -
Genotypic and phenotypic characterization of HIV-1 transmitted/founder viruses and their effect on cytokine profiles and disease progression among acutely infected Ugandans
(Makerere University, 2022)Virus-host interaction early after transmission elicit changes that are known to impact the course of the infection and clinical outcome. The nature of the virus that initiates the infection seems to play a key role. For ... -
Evaluation of contractile activity of the extracts of Gynandropsis gynandra Linn on isolated rabbit uterus and ileum
(Makerere University, 2022)Diarrhea due to exaggerated GIT motility and maternal death due to delayed labor remain serious health challenges; and among the leading causes of mortality globally especially among children and pregnant mothers respectively. ... -
Prevalence and histological types of kidney disease in autopsied persons at Kampala Capital City Authority Mortuary.
(Makerere University, 2022-02)Introduction: It is estimated globally that in 2016, 5-10 million people died from kidney dis-ease (KD) and about 1.7 million died from acute kidney injury. In sub Saharan Africa the prevalence of KD is quite high and is ... -
Expression of ARID1A in Penile Squamous Cell Carcinoma and its association with age, histological subtypes and grades in the Pathology Department, Makerere University.
(Makerere University, 2022-03)Background: About ninety-five percent (95%) of penile carcer arise in the squamous epithelium, giving rise to squamous cell carcinoma. Worldwide, the incidence and global health burden of penile cancer is in the range of ... -
Vegf protein expression in gastric cancer and associated clinical pathological features as seen at the Department of Pathology, Makerere University
(Makerere University, 2022-03-17)Background: Gastric cancer is the 5th most common cancer accounting for 5.7% of all cancers in the world and causes about 783,000 deaths annually. In Uganda the incidence of gastric cancer increased from 0.8 cases per ... -
BCL-2 protein expression in oral squamous cell carcinoma and associated clinicopathological features as seen at the Pathology Department, Makerere University
(Makerere University, 2021-11)Background: Predicting clinical behavior of oral squamous cell carcinoma based on histopathological analysis requires immunohistochemical supplementation with biomarkers like Bcl-2 protein that can be used in prognostic ... -
The evaluation of effect of canarium schweinfurthii leaf and pulp extracts on blood glucose levels in oral glucose load - induced hyperglycemia, heamatological parameters and safety in wistar albino rats
(Makerere University, 2022-03-14)Background: Canarium schweinfurthii (C. schweinfurthii) is a common medicinal plant in Uganda used as food and as medicine in the management of Diabetes mellitus type 2 and anemia by local communities and traditional ... -
Role of vaginal microbiome in host susceptibility to HIV infection among pregnant Ugandan women: inflammatory response and epithelial barrier integrity
(Makerere University, 2021-10)Background: Pregnant women are a key target population in the prevention of new HIV infections, and their protection can be extrapolated to their unborn children during pregnancy and at birth. The role of vaginal microbiota ... -
Participants’ understanding of informed consent for genomic research: a case of the CAfGEN study.
(Makerere University, 2020-07)Introduction: For informed consent to be valid, prospective participants are required to have adequate understanding of research prior to making decisions about participation. Studies have reported that participants in ... -
Magnitude of bilateral cataracts and factors associated with delayed uptake of cataract surgery among adult patients with operable cataract seen at Mulago Hospital.
(Makerere University, 2022-01-20)Background. Cataract is an opacity in the natural lens of the eye that causes visual impairment to vision of less than 6/9. Cataract causes 51% of global blindness and any delay in timely uptake of cataract surgery results ... -
Renal function of hospitalised adult patients with trauma at Mulago national referral hospital
(Makerere University, 2021-04-13)Globally trauma is the leading cause of death in persons aged 5 to 44 years and accounts for approximately 10% of all deaths in general. In Uganda more than 25% of all deaths recorded in urban areas are due to trauma. ... -
Translocation of rectal flora and its role in pathogenesis of septicemia in children with severe acute malnutrition
(Makerere University, 2018-12-06)Introduction: Childhood under-nutrition alters gut mucosal permeability and architecture, causing movement of organisms from GIT into circulation. Most studies carried have detailed bacteremia with malnutrition but none ... -
Molecular epidemiology of antimicrobial resistance at a human-animal interface in pastoralist community of Kasese District, Uganda
(Makerere University, 2021-04)Background: Intensive usage of antimicrobials in the management of animal diseases may cause selection for resistance among microorganisms. Transmission of resistant bacteria from the wild and domestic food animals to ... -
Host genetic variations and their association with malaria among Ugandan children
(Makerere University, 2021-04)This thesis comprises studies of the relationship between host genetic factors and incidence of uncomplicated malaria in a vaccine trial site in Iganga district. The studies focused on selected host gene markers that are ... -
Research participants’ perspectives on compensation for participation in biomedical research in cancer patients at Uganda Cancer Institute
(Makerere University, 2021-04-09)Background: Compensation of research participants in health-related research is a common practice that has existed globally for the last 100 years but is implemented differently in diverse research settings basing on generic ... -
Prevalence of immune non-response to Hepatitis B virus vaccine among secondary school students in Kumi district, Eastern Uganda
(Makerere University, 2021-05-11)Background: Hepatitis B virus is still a silent killer disease in Ugandan communities, particularly in high burdened regions. Despite Government initiative for mass vaccination program for those areas, there has been ...