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Non-linear mixed effects modeling of liver function biomarkers in TB-HIV patients co-treated with Rifampicin and Efavirenz based regimens
(2013-11)
Introduction
Survival has improved as a result of improved HIV therapy but liver disease remains a critical problem in HIV patients. HIV disease, ART and Tuberculosis treatments have all been documented to cause liver ...
Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study
(Elsevier, 2012-01-01)
Background Hormonal contraceptives are used widely but their eff ects on HIV-1 risk are unclear. We aimed to assess
the association between hormonal contraceptive use and risk of HIV-1 acquisition by women and HIV-1 ...
HIV/AIDS patients display lower relative bioavailability of Efavirenz than healthy subjects
(Adis Data Information BV., 2011)
Background: Pharmacokinetic studies of antiretroviral drugs are often conducted in adult healthy subjects, and the results are extrapolated to HIV/AIDS patients. HIV/AIDS, however, is known to cause morphological and ...
The International HIV Dementia Scale: a new rapid screening test for HIV dementia
(Lippincott Williams & Wilkins, 2005)
Objective: HIV dementia is an important neurological complication of advanced HIV infection. The use of a cross-cultural screening test to detect HIV dementia within the international community is critical for diagnosing ...
Incremental yield of serial sputum cultures for diagnosis of tuberculosis among HIV infected smear negative pulmonary TB suspects in Kampala, Uganda
(PLoS ONE, 2012-05-22)
Background: Sputum culture is the gold standard for diagnosis of pulmonary tuberculosis (PTB). Although mostly used for research, culture is recommended by the World Health Organization for TB diagnosis among HIV infected ...
Acceptance of routine counselling and testing for HIV among medical patients at Mulago Hospital casuality unit.
(2005-07)
Introduction: HIV counseling and testing is an entry point to comprehensive HIVIAIDS prevention and care. In Uganda, VCT is available in ambulatory settings where clients present by self-selection. Routine Counseling and ...
Treatment of chronic hepatitis B virus infection in resource-constrained settings: expert panel consensus
(John Wiley & Sons, 2010)
Most of the estimated 350 million people with chronic hepatitis B virus (HBV) infection live in resource-constrained settings. Up to 25% of those persons will die prematurely of hepatocellular carcinoma (HCC) or cirrhosis. ...
Sero-prevalence of herpes simplex type 2 virus (HSV-2) and HIV infection in Kampala, Uganda
(African Health Sciences, 2014)
Background:
Prevalence of herpes simplex type 2 virus (HSV-2) is high worldwide. Previous studies in Uganda were rural or in women.
We estimated age and sex-specific sero- prevalence of HSV-2 in Kampala, Uganda.
Methods: ...
Depression symptoms and cognitive function among individuals with advanced HIV infection initiating HAART in Uganda
(BMC Psychiatry, 2010)
Background: Among patients with HIV infection, depression is the most frequently observed psychiatric disorder. The presence of depressive symptoms and cognitive dysfunction among HIV patients has not been well studied in ...
When to switch for antiretroviral treatment failure in resource-limited settings?
(Lippincott Williams & Wilkins., 2007)
Thanks to the leadership of the World Health Organisation (WHO) [1], and massive financial support from programmes such as the Global Fund and the US President’s Emergency Plan for AIDS Relief (PEPFAR), the number of ...