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Research participants’ perspectives on compensation for participation in biomedical research in cancer patients at Uganda Cancer Institute
(Makerere University, 2021-04-09)
Background: Compensation of research participants in health-related research is a common practice that has existed globally for the last 100 years but is implemented differently in diverse research settings basing on generic ...
Renal function of hospitalised adult patients with trauma at Mulago national referral hospital
(Makerere University, 2021-04-13)
Globally trauma is the leading cause of death in persons aged 5 to 44 years and accounts for approximately 10% of all deaths in general. In Uganda more than 25% of all deaths recorded in urban areas are due to trauma. ...
Host genetic variations and their association with malaria among Ugandan children
(Makerere University, 2021-04)
This thesis comprises studies of the relationship between host genetic factors and incidence of uncomplicated malaria in a vaccine trial site in Iganga district. The studies focused on selected host gene markers that are ...
Molecular epidemiology of antimicrobial resistance at a human-animal interface in pastoralist community of Kasese District, Uganda
(Makerere University, 2021-04)
Background: Intensive usage of antimicrobials in the management of animal diseases may cause selection for resistance among microorganisms. Transmission of resistant bacteria from the wild and domestic food animals to ...
Role of vaginal microbiome in host susceptibility to HIV infection among pregnant Ugandan women: inflammatory response and epithelial barrier integrity
(Makerere University, 2021-10)
Background: Pregnant women are a key target population in the prevention of new HIV infections, and their protection can be extrapolated to their unborn children during pregnancy and at birth. The role of vaginal microbiota ...
Evaluation of the efficacy and safety of combining Carica Papaya Linn, Vernonia Amygdalina Delile, Artemisinin and Iodine as potential agents in the management of Breast Cancer
(Makerere University, 2021-12-25)
Background: Carica papaya Linn (CP), Vernonia amygdalina Delile (VA), dihydroartemisinin (DHA) and molecular iodine (I2) were reported to have antiproliferative and cytotoxic activities on breast cancer but their anticancer ...
In vitro activity of mycobacteriophages against Mycobacterium tuberculosis biofilms
(Makerere University, 2021-03)
Tolerance of Mycobacterium tuberculosis to antibiotics has been associated with its tendency to grow in cell aggregates known as biofilms. These biofilms consist of layers of cells covered by a lipid-rich extracellular ...
Stool-based xpert ultra testing for pulmonary tuberculosis in children in Kampala, Uganda
(Makerere University, 2021-02-25)
Background.. Globally, the diagnosis of tuberculosis (TB) in children is challenging principally
because of the paucibacillary nature of TB in children and the difficulty in obtaining good quality
sputum samples. More ...
Assessment of quality of raw bovine milk sold in Kampala City: A cross sectional study
(Makerere University, 2021-03)
Background: Recently there has been increasing reports concerning the safety of certain foods consumed in Uganda. Milk and meat sold on the Ugandan market have been reported to be contaminated with chemicals or adulterants ...
Determination of Interleukin 35 Levels as Inhibitory Cytokine in type 2 diabetic patients infected with latent tuberculosis at Mulago hospital, Uganda
(Makerere University, 2021-04-12)
Background: Mycobacterium tuberculosis (Mtb) remains a successful pathogen causing tuberculosis (TB), and the burden of TB disease is constantly increasing. Although great progress has been made in delineating the disease, ...